Perceptions and Knowledge of Dermatologic Side Effects of Anti-Cancer Therapies: A Pilot Survey

August 2025 | Volume 24 | Issue 8 | e57 | Copyright © August 2025


Published online July 30, 2025

Nikita Menta BAa, Savanna I. Vidal BSa, Cleo Whiting BAa, Sara Abdel Azim MSb, Sapana Desai MDa, Adam Friedman MD FAADa

aDepartment of Dermatology, George Washington University School of Medicine and Health Sciences, Washington, DC
bGeorgetown University School of Medicine, Washington, DC

Abstract

INTRODUCTION

Anti-cancer therapies (ACTs) cause physically and psychosocially distressing dermatologic side effects (DSEs) that occasionally necessitate dose reduction or treatment discontinuation.1 While their psychological impact is well-established, limited data exist on public perceptions and knowledge of DSEs.

To evaluate knowledge and perceptions of ACT DSEs in a medically underserved community, an IRB-approved survey (#NCR191384) was offered to all attendees (>18 years) at two health fairs in Southeast Washington, D.C., the most medically underserved area of the district. ACT was defined as any anticancer medication and/or radiation. Assessed DSEs included hair loss (HL), dry skin/rash, and nail changes (NCs). The survey was completed by 77 attendees (65% response). The majority were female (88.3%), 45-54 years old (23.7%), and Black or African American (71.5%). Twenty-one percent of respondents were previously treated for cancer.

Most respondents believed that ACTs cause HL (52% [all respondents] vs 31% [respondents previously treated for cancer]), dry skin/rash (47% vs 50%), and NCs (41% vs 31%) more than half the time (Figure 1). The DSEs that respondents most frequently reported would make them possibly/definitely not undergo treatment were permanent HL (33% vs 13%), temporary eyebrow/eyelash HL (27% vs 13%), and permanent nail discoloration (24% vs 13%; Figure 2). Notably, half of the patients who were previously treated for cancer did not visit a dermatologist during cancer treatment.