National Institutes of Health Funding for Vitiligo Research: Trends from 1985 to 2024

December 2025 | Volume 24 | Issue 12 | 9011 | Copyright © December 2025


Published online November 18, 2025

Abdulaziz Hamid BSa, Kara Turner BAb, Nada Elbuluk MD MScc

aMedical College of Wisconsin, Milwaukee, WI
bAlbert Einstein College of Medicine, Bronx, NY
cDepartment of Dermatology, University of Southern California Keck School of Medicine, Los Angeles, CA

Abstract
Background: The National Institutes of Health (NIH) funds a multitude of dermatology research. This study examines NIH funding for vitiligo studies and highlights key trends.
Methods: The NIH Research Portfolio Online Reporting Tool database was used to identify vitiligo research projects funded between 1985 and 2024, with results limited to project titles containing "vitiligo."
Results/Discussion: The NIH awarded 166 grants for vitiligo research between 1985 and 2024. This study analyzed 144 of these awards, totaling $22,343,119. The greatest increase occurred between 1998 and 1999, with the average funding per grant rising by $124,316, leading to a total funding increase from $269,102 to $1,149,554. The most common funding mechanism was Non-Small Business Innovation Research (SBIR)/Small Business Technology Transfer (STTR). The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) was the leading administering institute. Medical schools were the most awarded organization type. The most common grant types were R01 (n=59, 41%) and M01 (n=21, 15%). Among the 144 funded projects, 48 were unique, with most focusing on pathophysiology (n=36) and treatment (n=8).
Limitations: Study limitations include incomplete data on NIH research funding, with 22 awards missing total cost information and 25 awards calculated using subproject sums.
Conclusion: From 1985 to 2024, NIH funding for vitiligo research fluctuated with an upward trend in recent years. The most common funding mechanism was Non-SBIR/STTR. Among organization types, medical schools received the most awards. Most vitiligo research projects have been completed and have focused on understanding the pathophysiology and treatment of vitiligo.

 

INTRODUCTION

Vitiligo research has seen a gradual increase in publications and citations from 1980 to 2000, with a significant rise after 2005.1 Vitiligo research peaked in 2016 with 528 published articles and in 2017 with 10,390 citations. The most cited works are original articles from the United States, focusing on melanoma, autoimmunity, and immunotherapy.1 To guide future research and funding opportunities, this study evaluated trends in National Institutes of Health (NIH) funding of vitiligo research.

The NIH Research Portfolio Online Reporting Tool database was used in July 2024, to identify projects funded between fiscal years 1985 and 2024, limiting the search to project titles containing "vitiligo".2 Information was collected on the project title, project number, administering institutes or centers (ICs), department, organization name, organization city, organization state, organization type, organization country, grant type, project start and end dates, funding mechanism, fiscal year, total cost, total cost (sub projects), funding IC(s), direct cost IC, indirect cost IC, and total cost IC. NIH funding amounts have been adjusted to 1985 US dollars to account for inflation using Consumer Price Index data from the Bureau of Labor Statistics.3

The NIH awarded 166 vitiligo research awards between 1985 and 2024. This study analyzed 144 of these awards, totaling $22,343,119. Vitiligo research funding has fluctuated over the years, but in recent years shows an upward trend. The greatest increase occurred between 1998 and 1999, with the average funding per grant increasing by $124,316, leading to a total funding increase from $269,102 to $1,149,554 (Figure 1).2