INTRODUCTION
Rosacea is a chronic, inflammatory dermatosis primarily affecting the central face that affects approximately 10% of adults,1,2 with higher rates in women and those with Fitzpatrick skin Types I to II.1,3,4 Onset of rosacea most often occurs after age 30; however, it may occur at any age and is characterized by repeated remissions and exacerbations.5 Characteristics of clinical manifestations dictate treatment decisions for rosacea, and several topical pharmacological interventions are indicated for the treatment of mild to moderate rosacea.1
First-line treatment options for mild to moderate rosacea typically include metronidazole and azelaic acid. These therapies have demonstrated efficacy compared to placebo in reducing inflammatory lesions but with increasing incidence of topical irritations. Given the availability of multiple agents with proven efficacy, clinicians and patients may consider additional information to guide therapeutic decision-making, including side effect profile and a treatment’s effect on quality of life (QoL).
Previous research has shown that rosacea patients initiated on topical therapies who experience side effects are likely to discontinue treatment: ~90% discontinue within the first 3 months of therapy.6 Currently, there is a lack of head-to-head trials comparing treatment satisfaction among rosacea patients using the first-line treatment options for mild to moderate rosacea: metronidazole gel (MG), metronidazole cream (MC), and azelaic acid 15% foam (AAF) (Finacea® Foam, Bayer).
Two independently conducted treatment studies assessed patient preference with ongoing rosacea treatment.7,8 In each
First-line treatment options for mild to moderate rosacea typically include metronidazole and azelaic acid. These therapies have demonstrated efficacy compared to placebo in reducing inflammatory lesions but with increasing incidence of topical irritations. Given the availability of multiple agents with proven efficacy, clinicians and patients may consider additional information to guide therapeutic decision-making, including side effect profile and a treatment’s effect on quality of life (QoL).
Previous research has shown that rosacea patients initiated on topical therapies who experience side effects are likely to discontinue treatment: ~90% discontinue within the first 3 months of therapy.6 Currently, there is a lack of head-to-head trials comparing treatment satisfaction among rosacea patients using the first-line treatment options for mild to moderate rosacea: metronidazole gel (MG), metronidazole cream (MC), and azelaic acid 15% foam (AAF) (Finacea® Foam, Bayer).
Two independently conducted treatment studies assessed patient preference with ongoing rosacea treatment.7,8 In each