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Optimizing Patient Adherence: Update onCombination Acne Therapy—Teens and Beyond

June 2010 | Volume 9 | Issue 6 | Department | 86 | Copyright © June 2010


Brad A. Yentzer MD, Hilary Baldwin MD, Alan R. Shalita MD, Guy Webster MD, Steven R. Feldman MD PhD

Abstract
Acne vulgaris can cause both physical and emotional scarring. Effective treatment requires an understanding of acne pathogenesis and the key elements of keratinocyte differentiation and comedone formation, sebum production, colonization with Propionibacterium acnes (P. acnes) and subsequent inflammation. Addressing issues of compliance is critical for good outcomes, and newer combination therapies help improve adherence to daily therapy.