Correction of Atrophic Scars With Artefill: An Open-label Pilot Study
September 2010 | Volume 9 | Issue 9 | Original Article | 1062 | Copyright © September 2010
Rachel E. Epstein DO and James Spencer MD MS
Background: Artefill®, a novel permanent filler approved by the U.S. Food and Drug Administration (FDA), has been used as an injectable
implant for the correction of nasolabial folds. Fillers are considered a first line treatment for atrophic scars.
Objective: The authors evaluated the degree of correction and subject satisfaction of correction of atrophic acne scar(s) after injection
Methods: Fourteen qualified subjects participated in a single-center, open-label, pilot study. Atrophic acne scars were evaluated prior
to injection. Subscision was performed, and then Artefill was injected into the scar. The degree of improvement was measured at
weeks 2 and 4 and month 8. Subjects were asked to fill out a satisfaction survey at their eight-month visit.
Results: Investigator ratings after eight months post procedure indicated that 96 percent of the atrophic acne scars showed some
degree of improvement. There was no improvement in two out of a total of 57 scars evaluated. The majority of patients reported a
moderate correction, correlating with a 51–75 percent improvement in their acne scars at eight months. No adverse events or side
effects were noted.
Conclusion: Artefill demonstrated to be both an efficacious and safe therapy for the treatment of atrophic acne scars.