Treating Photodamage of the Décolletage Area With a Novel Copper Zinc MalonateComplex Plus Hydroquinone and Tretinoin
March 2010 | Volume 9 | Issue 3 | Original Article | 220 | Copyright © March 2010
James J. Leyden MD and Lisa Parr PharmD
Treatment was associated with early and significant (P≤0.05) improvements in mean scores on an overall integrated assessment of photodamage (from week 4 onward) and for multiple signs of photodamage—tactile roughness (from week 2 onward); mottled hyperpigmentation, lentigines and fine wrinkling (from week 4 onward); laxity (from week 8 onward); and crepiness and coarse wrinkling (from week 12 onward). Treatment was generally well tolerated and 94% of subjects were satisfied or very satisfied with the overall improvement in their décolletage at week 24.