Long-Term Evaluation of Collagen and Elastin Following Infrared (1100 to 1800 nm) Irradiation
August 2009 | Volume 8 | Issue 8 | Original Article | 708 | Copyright © August 2009
Yohei Tanaka MD, Kiyoshi Matsuo MD PhD, Shunsuke Yuzuriha MD PhD
Objective: To investigate the effects of infrared irradiation.
Methods and Materials: In vivo human tissues in sun-protected and sun-exposed areas were irradiated with infrared. Histological samples were analyzed, and visual changes were assessed up to 90 days post-treatment.
Results: Infrared irradiation provided long-term increases in collagen and elastin levels on post-irradiation days 30, 60 and 90 compared to controls. Significant increases in type I collagen persisted until 30 and 60 days, and in sun-protected and exposed skin biopsies, respectively. Significant increases in type III collagen and elastin persisted until 90 days in both sun-protected and sun-exposed skin biopsies.
Conclusion: Infrared irradiation provides safe and effective long-term stimulation of collagen I and III and elastin, which is beneficial for improving skin laxity and wrinkles.