Antibiotic Selection of MRSA: Case Presentations and Review of the Literature
March 2009 | Volume 8 | Issue 3 | Case Reports | 281 | Copyright © March 2009
Matthew R. Hanson MD, Christina L. Chung MD
Infection with methicillin-resistant Staphylococcus aureus (MRSA) is a growing presence in both the community and hospital settings.
Initially, MRSA was a difficult to treat infection isolated to hospitalized patients. With the introduction of vancomycin and other
newer antibiotics, successful treatment of nosocomial, or hospital-acquired MRSA (HA-MRSA) has become commonplace. More
recently, MRSA has evolved independently in each community. These community-acquired MRSA (CA-MRSA) strains initially had
more limited resistance profiles, but selective pressures have broadened the resistance in many areas. Given the evolution in resistance
among MRSA isolates, choosing an appropriate antibiotic therapy is challenging. Here the authors present 3 cases of HA- and
CA-MRSA from an inner-city, tertiary care center and review recent literature with regards to antibiotic selection and administration.