Severe Reaction to 5% Imiquimod Cream with Excellent Clinical and Cosmetic Outcomes
April 2007 | Volume 6 | Issue 4 | Case Reports | 452 | Copyright © April 2007
H.L. Greenberg MD, Joel L. Cohen MD, Ted Rosen MD, Ida Orengo MD
Imiquimod, an immune response modifier approved for the treatment of external genital warts, actinic keratoses, and superficial
basal cell carcinoma, can induce a severe local inflammatory response. This phenomenon can accompany inappropriately
overzealous, as well as entirely conventional, drug utilization. Despite strikingly brisk reactions, the 9 patients
reported herein ultimately experienced excellent cosmetic and clinical outcomes. We report this series to alert clinicians
of the good prognosis for a satisfactory outcome even when faced with extreme imiquimod cream-induced inflammation.