Eosinophilic Granuloma of the Skin: Response to Intralesional Corticosteroid Injection
March 2007 | Volume 6 | Issue 3 | Case Reports | 329 | Copyright © March 2007
Vesna Petronic-Rosic MD MSc, Elizabeth Myers, Christopher R. Shea MD, Thomas Krausz MD
Langerhans cell histiocytosis (LCH) is a histiocytic disorder in which the Langerhans cell is arrested in a premature, partially
active state. The disease comprises a spectrum of disorders, the most benign of which is a single-system unifocal disease.
Lesions in single-system LCH are typically limited to the bone. We report a case of a 66-year-old man with a
single-system disease limited to the skin, who was successfully treated with intralesional triamcinolone. This minimally
invasive treatment method warrants further studies of intralesional corticosteroid injection for skin lesions of LCH.