Primary Cutaneous Nodular Amyloidosis in a Patient with Sjögren’s Syndrome7
March 2006 | Volume 5 | Issue 3 | Case Reports | 279 | Copyright © March 2006
Monika Srivastava MD
A 71-year-old woman with a history of Sjögren’s syndrome presented for evaluation of a waxy nodule present on the scalp for
6 months. Histopathologic examination revealed deposition of homogenous eosinophilic material throughout the reticular
dermis consistent with amyloidosis. Primary cutaneous nodular amyloidosis is a rare phenomenon characterized by the deposition
of immunoglobin light chains by a clonal plasma cell population. Patients need to be monitored for progression to
systemic amyloidosis or plasma cell dyscrasias.