Bullous Pemphigoid following Therapy with an Oral Beta-Blocker
November 2005 | Volume 4 | Issue 6 | Case Reports | 746 | Copyright © November 2005
2LT Adam Perry MSC USAF, CPT Joshua D. Sparling MC USA, LCDR Mark Pennington MC USN
A causal relationship is thought to exist between several medications and the development of bullous pemphigoid.
Commonly implicated medications include furosemide, penicillins, and ibuprofen. The following is a case report of an
elderly man who developed generalized bullous pemphigoid for the first time after beginning therapy with an oral betablocker.
A literature search revealed only 2 other reports of beta-blocker associated bullous pemphigoid. As both bullous
pemphigoid and beta-blockers are common in elderly patients, dermatologists may want to consider beta-blockers
as potential etiological agents in the development of bullous pemphigoid.