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Dec 10
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Afamelanotide: An Orphan Drug with Potential for Broad Dermatologic Applications

By No Comments
INTRODUCTIONAfamelanotide (SCENESSE®) is a synthetic analogue of α‐melanocyte‐stimulating hormone (α-MSH) that induces tanning of the skin. α-MSH is a product of the proopiomelanocortin gene (POMC), which is cleaved into the…
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Dec 10
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Adding Combined Oral Contraceptives or Metformin to Laser Treatment in Polycystic Ovarian Syndrome Hirsute Patients

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INTRODUCTIONHirsutism is defined as the growth of excessive terminal hair in androgen-dependent sites in females.1 Hirsutism affects 10% to 20% of women,2 having a major impact on their quality of…
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Dec 10
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Successful Treatment of Lichen Amyloidosis Using a Fixed Combination of Halobetasol-Propionate and Tazarotene Lotion

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INTRODUCTIONLichen amyloidosis is characterized by “rippled”, brown, extremely pruritic plaques, typically on the lower extremities, that is often refractory to medical intervention. Here, a case of lichen amyloidosis successfully treated…
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Dec 10
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A Multi-Centered Case-Control Study of Vitiligo Support Groups and Quality of Life

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INTRODUCTIONVitiligo is an acquired chronic autoimmune cutaneous pigmentary disease of the skin, affecting nearly 1-2% of the population worldwide.1 The disease causes destruction of melanocytes and is characterized by depigmented…
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Dec 10
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Vitiligo Health Education: A Study of Accuracy and Engagement of Online Educational Materials

By No Comments
INTRODUCTIONVitiligo is a chronic autoimmune disorder affecting an estimated 0.5–2% of the worldwide population.1 It is characterized by the loss of pigmentation of the skin and overlying hair due to…
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Dec 10
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Delayed Onset of Alcohol-Induced Flushing Following Chronic Topical Tacrolimus Application

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INTRODUCTIONA 48-year-old white woman presented with a twelvemonth history of intermittent pruritic pink facial papules and two months of alcohol-induced circumscribed centrofacial flushing. She reported applying tacrolimus 0.03% ointment nightly…
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Dec 10
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Hand Foot Skin Reaction Associated With Palbociclib

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INTRODUCTIONPalbociclib is one of three new small-molecule inhibitors of cyclin-dependent kinase 4 and 6 (CDK4/6) approved for use in the treatment of hormone receptor positive (HR+) and human epidermal growth…
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Dec 10
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Characterizing Dermatology Interest Groups (DIGs) in US Medical Schools: A Nationwide Survey of Student Leaders

By No Comments
INTRODUCTIONFor many medical students, specialty interest groups provide first exposures and help generate interest in various medical specialties. Specialty interest groups also serve as important resources for gaining information and…
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Dec 10
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Impact of Laboratory Work Up and Supplementation on Alopecia Patients: A Single-Center Retrospective Chart Review

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INTRODUCTIONNon-scarring alopecia is the most common presentation regarding hair loss. Evaluation of alopecia often includes laboratory testing for ferritin, thyroid stimulating hormone (TSH), vitamin D, and zinc, as previous studies…
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Dec 10
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Treatment Dissecting Cellulitis of the Scalp With Secukinumab

By No Comments
INTRODUCTIONDissecting cellulitis of the scalp (DCS), also known as perifolliculitis capitis abscedens and suffodiens, is a form of neutrophilic cicatricial alopecia leading to irreversible hair loss.1 It presents with pustules,…
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Dec 10
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Cost Trends of Hydroquinone and Other Dyschromia Treatments in the United States

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INTRODUCTIONSkin dyspigmentation is a common dermatologic concern, particularly in patients with skin of color.1 Hydroquinone is often used as a first-line therapy for dyschromia, and is approved for treatment of…
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Dec 10
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Pediatric Lichen Planopilaris Treated With Pioglitazone: A Case Study and Literature Review

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INTRODUCTIONLichen planus (LP) is an inflammatory papulosquamous dermatosis occurring in children in only 10–11% of cases.1 Lichen planopilaris (LPP) is a clinical variant of LP that demonstrates lymphocytic scarring alopecia.2…
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