INTRODUCTIONDisseminate and recurrent infundibulofolliculitis (DRIF) is a rare skin condition of unknown etiology first reported by Hitch and Lund in 1968.1 In our clinical practice, we have encountered this condition…
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INTRODUCTIONAmong the major subtypes of melanoma, nodular melanoma is associated with the poorest prognosis.1 Nodular melanoma can be further subdivided into distinct variants, among which the polypoid (pedunculated) tumor has…
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INTRODUCTIONChromate, an anion of chromium and oxygen discovered by Vaquelin in 1798, is a common cause of occupational skin disease.1 The prevalence of chromium sensitivity in the general U.S. population…
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INTRODUCTIONThe term tumescence, by definition, is the state of being swollen. When we speak of tumescent anesthesia, we broaden this to include swollen tissue with various amounts of analgesics and…
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INTRODUCTIONCysteamine is an aminothiol naturally present in cells of the human body as an antioxidant resulting from the degradation of Coenzyme A.1 Physiological levels are well distributed in mammalian tissues.…
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INTRODUCTIONTrichilemmal cysts (TCs) are the most common cystic lesions arising on the scalp and up to 2% give rise to a proliferating trichilemmal tumor (PTT). A rare subset of PTTs…
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INTRODUCTIONRaynaud’s phenomenon (RP), a common presenting symptom of systemic sclerosis (SSc), is a painful and debilitating condition of the digits caused by increased vascular reactivity.1,2 Recurrent digital ulcers and critical…
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INTRODUCTIONPalmoplantar pustulosis (PPP) is a chronic, debilitating autoimmune skin disease characterized by the presence of recurrent neutrophilic pustules on acral surfaces. Although similarities exist, PPP is currently regarded as a…
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INTRODUCTIONCccording to Mimouni et al, dermatology publication trends from 1993 to 2007 revealed a faster increase in high level of evidence studies such as clinical and randomized controlled trials, and…
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INTRODUCTIONThis year, 2021, is the 50th anniversary since the 1971 FDA approval of minocycline (MCN) and its introduction into the dermatologist’s toolbox. Over those same 50 years, multiple antibiotics have…
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INTRODUCTIONPalmoplantar pustulosis (PPP) is a psoriasis subtype characterized by small sterile pustules or blisters with hyperkeratosis, erythema, scaling, and fissuring on the palms and/or soles, along with itching and burning…
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The combination of Interferon-α-2b (IFN-α-2b) and phototherapy is highly effective in treating mycosis fungoides (MF) but side effects often lead to discontinuation of therapy.1 The development of pegylated interferon-α-2b (PEG-IFN-α-2b),…
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