INTRODUCTIONPsoriasis is a common chronic inflammatory disease affecting 2-4% of the adult population worldwide, with one-third of patients having moderate-to-severe psoriasis.1-4 The development of targeted and highly effective biological systemic…
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INTRODUCTIONRecent studies revealed the importance of gut microbiota in body health conditions.1 Understanding the gut microbiome started a new field of study that emphasizes the potential biochemical mechanisms of the…
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INTRODUCTIONWe read with great interest the recent publication by Fölster-Holst et al1 in the May issue of Journal of Drugs in Dermatology, which offered a brief update on the treatment…
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INTRODUCTIONDisparities and inequities exist in dermatological access and outcomes, associated with demographics such as socioeconomic status (SES) and geography.1,2 Some studies have documented barriers to care and treatment adherence in…
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INTRODUCTIONImmune checkpoint inhibitors including programmed death protein 1 (PD-1) inhibitors show great therapeutic benefit for numerous advanced malignancies, but cause a spectrum of immune-related adverse events (irAEs), with cutaneous toxicity…
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INTRODUCTIONLichen planopilaris (LPP) is a cicatricial alopecia that presents with patchy or diffuse hair loss at the vertex or parietal scalp. Although there is no gold standard therapy, most interventions…
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INTRODUCTIONMohs micrographic surgery (MMS) is typically associated with mild to moderate pain on the day of surgery and first postoperative day that is often well-managed with over the counter analgesics.1…
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INTRODUCTIONHyperhidrosis (HH) is a disorder of eccrine sweat production in an amount in excess of what is needed for thermoregulation. It is estimated that HH affects 4.8% of the US…
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INTRODUCTIONSARS-CoV-2 infection has been associated with a variety of changes in the nail unit,1 namely nail fold capillary changes,2 pernio-like changes known as COVID-toes or COVID-fingers3-5 positive for SARS-CoV-2 in…
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INTRODUCTIONImmunosuppression, as seen in solid organ transplant recipients (SOTRs), has been highly associated with the development of cutaneous keratinocyte carcinomas (KCs), particularly squamous cell carcinomas (SCCs) and basal cell carcinomas…
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INTRODUCTIONNivolumab is a human immunoglobulin monoclonal antibody IgG4 that binds to and thus blocks the programmed death (PD-1) receptor, and ipilimumab is a monoclonal antibody against CTL antigen 4 (CTLA-4).…
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INTRODUCTIONOn histologic interpretation during MMS, the authors observed numerous areas of incompletely stained tissue where cellular architecture was preserved, but obscured by an amorphous, eosinophilic artifact that eliminated contrast between…
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