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Mar 14
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Open-Label Phase 2 Pilot Study of Oral Tofacitinib in Adult Subjects With Discoid Lupus Erythematosus (DLE)

By Chuck Lin No Comments
INTRODUCTIONDiscoid lupus erythematosus (DLE) is a chronic inflammatory skin disease that occurs with or without systemic lupus erythematosus (SLE). DLE treatment is challenging, and there is paucity of effective therapeutic…
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Mar 07
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Dupilumab Induced Hair Regrowth in Alopecia Totalis

By Chuck Lin No Comments
INTRODUCTIONAlopecia areata (AA) is a form of non-scarring alopecia that results from an autoimmune process that targets hair follicles.1 The severity of the disease varies from a focal, patchy hair…
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Feb 21
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Reversal of Stress-Associated Alopecia

By Chuck Lin No Comments
INTRODUCTIONNovel coronavirus SARS-CoV-2, designated as COVID-19 by the World Health Organization (WHO) on February 11, 2020, is one of the highly pathogenic β-coronaviruses that infects humans.1 Alopecia areata (AA) is…
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Feb 21
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Managing Monkeypox Virus: Characterizing Common Cutaneous Manifestations and Antiviral Efficacy

By Chuck Lin No Comments
INTRODUCTIONHuman monkeypox (MPX) is caused by an orthopoxvirus similar to the variola virus (smallpox) and was initially discovered in central Africa in 1970 affecting impoverished communities. It typically presents with…
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Feb 17
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Topical Minoxidil Adherence in Patients With Alopecia

By Chuck Lin No Comments
INTRODUCTIONAlopecia is a chronic debilitating disease. Topical minoxidil is the only FDA-approved treatment for both female and male pattern hair loss (androgenetic alopecia); it is also used off-label to treat…
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Feb 17
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DermTok: How TikTok Is Changing the Landscape of Dermatology Patient Education

By Chuck Lin No Comments
INTRODUCTIONThe role of social media in patient education continues to grow; approximately 80% of internet users in the United States have searched online for health information.1 With this growth, there…
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Feb 17
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Utilization Management Barriers Among Patients With Cicatricial Alopecia

By Chuck Lin No Comments
INTRODUCTIONCicatricial (scarring) alopecia leads to irreversible hair loss.1 Patients with scarring alopecia experience a high burden of psychosocial disease.1 While scarring alopecia can be difficult to treat, successful treatment can…
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Feb 17
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Melatonin and the Human Hair Follicle

By Chuck Lin No Comments
INTRODUCTIONMelatonin is synthesized primarily in the pineal gland, and in several extra-pineal sites including the retina, skin, bone marrow, cerebellum, and gastrointestinal tract.1 Melatonin acts primarily via G-protein coupled membrane…
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Feb 13
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Successful Management of Erythema Dyschromicum Perstans Following Topical Ruxolitinib Therapy

By Chuck Lin No Comments
INTRODUCTIONErythema dyschromicum perstans (EDP) is a rare cutaneous condition characterized by gray or blue-brown macules or patches that usually presets over the trunk, neck, and extremities.1 EDP occurs in both…
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Jan 30
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Shining Light on PDT and Actinic Keratosis

By Chuck Lin No Comments
Photodynamic therapy (PDT) is a non-invasive treatment modality involving photosensitizers that are activated by absorption of visible light to initially form the excited singlet state, followed by transition to the…
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Jan 27
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Graham-Little-Piccardi-Lasseur Syndrome: A Case Report

By Chuck Lin No Comments
INTRODUCTIONGraham-Little-Piccardi-Lasseur Syndrome (GLPLS) is a rare clinical subtype of lichen planopilaris (LPP) that manifests as a triad of scarring alopecia of the scalp, nonscarring alopecia of the axillary and the…
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Jan 24
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Differential RNA Transcriptome in Ustekinumab Responders vs Non-Responders

By Chuck Lin No Comments
CASEDespite numerous available psoriasis treatments, no "one size fits all"' regimen provides complete disease control without side effects, logistical obstacles, and/or expense. Despite increasingly efficacious drugs, only 20-25% of patients…
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