JDD Special Focus

Acne Supplements

Stay up-to-date on new clinical findings on Acne. View the latest articles, case reports, editorial features, supplements, Podcast episodes and more!

 

Supplements

Acneceuticals Maximized Therapeutic Outcomes in a Real-World Setting

Acne is the most common cutaneous disease worldwide and the most frequent disorder to present to the dermatology practice. Although efficacious treatments exist, clinicians continue to search for better regimens with improved safety for our patients. 

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Topical Acne Treatment: What’s Behind the Scenes in 2024

Optimal topical acne treatments should ideally target multiple pathways involved in acne development.2  Traditional treatments, though often effective, may come with limitations such as skin irritation, dryness, or other adverse effects. Thus, the pursuit of optimal topical acne treatments is critical to enhancing efficacy, minimizing side effects, and improving patient adherence and satisfaction.

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Advancements in Topical Combination Products for Acne Treatment

Antibiotic resistance and treatment adherence remain significant challenges for acne treatment. Advances in topical formulations have ushered in an era of fixed combination topical therapeutics that are well-tolerated and more efficacious. In addition, their once-daily application leads to increased treatment adherence. This article discusses formulation strategies that allow for the coadministration of active drugs and reviews all commercially available fixed-combination topical acne treatments.

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Tretinoin Formulation: From Microsponges to Polymeric Emulsion

The history of tretinoin and its use in dermatology is a testament both to the drug’s well-established efficacy and its potential to cause skin irritation. Over more than four decades, the drug that launched the retinoid class into the market has been used in the topical management of acne, either alone or in combination.

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Targeting Acne Pathogenesis with Topical Therapies

We, as dermatologists, are exceedingly lucky.  We can watch our patients improve before our eyes. In clinical practice, we don’t often track a quantitative metric to gauge success but rather measure the success of our treatment by the appearance of our patients’ skin.

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Podcast Episodes

Ask the Investigator: Acne, OCPs, and a Side Order of Practical Pearls for the Adolescent Patient

JDD Podcast host Dr. Adam Friedman gets first-hand insight from internationally acclaimed pediatric dermatologist Dr. Lawrence Eichenfield on his recent study entitled “Hormonal Contraceptives and Acne: A Retrospective Analysis of 2147 Patients” published in the June 2016 edition of the Journal of Drugs of Dermatology. Want a refresher on the use of OCPs in Acne?

Interested in learning how to initiate a patient based survey study? Just curious how a leader in the field gets an uninterested adolescent to be compliant and engaged in his/her acne care? These are just a few of the practical pearls provided.

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Featured Case Report

Efficacy and Safety of Sarecycline, a Novel, Once-Daily, Narrow Spectrum Antibiotic for the Treatment of Moderate to Severe Facial Acne Vulgaris: Results of a Phase 2, Dose-Ranging Study

There is a need for new oral antibiotics for acne with improved safety profiles and targeted antibacterial spectra. Sarecycline is a novel, tetracycline-class antibiotic specifically designed for acne, offering a narrow spectrum of activity compared with currently available tetracyclines, including less activity against enteric Gram-negative bacteria. This phase 2 study evaluated the efficacy and safety of three doses of sarecycline for moderate to severe facial acne vulgaris.

 

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Featured Editorial

Virtual Exams No Substitute for In-Person Care of Acne and Rosacea

Some dermatologists may be surprised to hear that the concept of teledermatology originated 25 years ago, and has slowly increased in usage, primarily for the purpose of providing care to those in underserved areas.1 The challenges created by the COVID19 pandemic has rapidly accelerated both interest and usage of telemedicine by dermatologists, with the American Academy of Dermatology and other dedicated groups responding quickly to provide guidance on how to integrate teledermatology into real-world dermatology practice effectively, and hopefully with avoidance of technical, medicolegal, and financial pitfalls.2
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Dermatology News

AcneFeatured ArticlesLatest NewsThe Latest
September 25, 2025

From the Vault: Integrated Short-Term and Long-Term Efficacy of Topical Clascoterone Cream 1% in Patients Aged 12 Years or Older With Acne Vulgaris

Clascoterone Keeps Gaining Ground in Acne Two identical Phase 3 trials (plus a long‑term extension) randomized patients ≥12 years with moderate‑to‑severe acne to twice‑daily clascoterone 1% cream or vehicle for…
Journal of Drugs in Dermatology JDD Article About Microneedling Combined With Drugs and Stem Cells for Treating Androgenetic AlopeciaAlopeciaFeatured ArticlesLatest NewsThe Latest
September 24, 2025

Microneedling Combined With Drugs and Stem Cells for Treating Androgenetic Alopecia

Small Channels, Smarter Delivery -  A Practical Boost For Topical And Regenerative Approaches Microneedling is proving to be a low‑risk, clinic-friendly way to enhance topical therapies (most consistently 5% minoxidil, now…
Journal of Drugs in Dermatology JDD Article About The Prevalence of Dupilumab-Associated Adverse Events Among Black and African American Adult Patients With Atopic Dermatitis: A Retrospective Chart ReviewAtopic DermatitisFeatured ArticlesLatest NewsThe Latest
September 24, 2025

The Prevalence of Dupilumab-Associated Adverse Events Among Black and African American Adult Patients With Atopic Dermatitis: A Retrospective Chart Review

Dupilumab in Diverse Skin — Are Adverse Events Really the Same? Atopic dermatitis isn’t one-size-fits-all: chronic type 2 inflammation, barrier dysfunction, and S. aureus colonization are core features, but presentation…
Journal of Drugs in Dermatology JDD featuring Dr. Jacob Beer in JDD Re:View, a discussion of JDD articles and specific topics. Aesthetic treatments are evolving faster than ever, from fillers and sunscreens to the promise (and debate) of exosomes. This month’s Re:View spotlights the studies shaping today’s practice and tomorrow’s possibilities.AestheticsFeatured ArticlesJDD Re:ViewLatest NewsThe Latest
September 23, 2025

JDD Re:View With Dr. Beer

Aesthetic treatments are evolving faster than ever, from fillers and sunscreens to the promise (and debate) of exosomes. This month’s Re:View spotlights the studies shaping today’s practice and tomorrow’s possibilities.…