Found 13 articles for: "distal subungual"
Individual Article: Updated Review of Topical Pharmaceuticals and Complementary and Alternative Medications for the Treatment of Onychomycosis in Both General and Special Populations in the United States
September 2023 | Volume 22 | Issue 9 | Supplement Individual Articles | SF378719 | Copyright © September 2023
Onychomycosis is a prevalent condition affecting the United States and global population. Treatment options are limited, with only 3 topical anti-fungal medications garnering approval in the US w...
Read MoreTherapeutic Recommendations for the Treatment of Toenail Onychomycosis in the US
October 2021 | Volume 20 | Issue 10 | Original Article | 1076 | Copyright © October 2021
Background: Onychomycosis affects around 14% of individuals in North America and Europe and is undertreated. Treatment is challenging as toenail growth can take 12–18 months, th...
Read MoreSafety, Pharmacokinetics, and Efficacy of Efinaconazole 10% Topical Solution for Onychomycosis Treatment in Pediatric Patients
September 2020 | Volume 19 | Issue 9 | Original Article | 867 | Copyright © September 2020
Background: Pediatric onychomycosis management is challenging as there are limited treatment options. The objective of this study was to evaluate efinaconazole 10% topical solution in...
Read MoreTavaborole 5% Topical Solution for the Treatment of Toenail Onychomycosis in Pediatric Patients: Results from a Phase 4 Open-Label Study
February 2019 | Volume 18 | Issue 2 | Original Article | 190 | Copyright © February 2019
BACKGROUND: This study was designed to evaluate the safety, tolerability, pharmacokinetics (PK), and efficacy of tavaborole in pediatric patients. Study Design: In this open-label, single-arm study, ...
Read MorePlanimetric Post-hoc Analysis of Women With Onychomycosis from Tavaborole 5% Phase III Studies: Evidence of Greater Improvements in Patients With >50% Baseline Infection
February 2018 | Volume 17 | Issue 2 | Original Article | 168 | Copyright © February 2018
Women with onychomycosis may suffer more effects on their quality of life than men. There is limited female-specific data on the treatment of onychomycosis. Tavaborole is a topical treatment option fo...
Read MoreTavaborole in Difficult-to-Treat Onychomycosis Cases: A Post-hoc Assessment of Phase III Subjects
October 2017 | Volume 16 | Issue 10 | Original Article | 1016 | Copyright © October 2017
Toenail onychomycosis is a chronic fungal infection that often requires prolonged treatment in order to effectively manage pathogenic organisms and obtain a clear nail. Traditionally, certain clinical...
Read MorePediatric Onychomycosis: The Emerging Role of Topical Therapy
February 2017 | Volume 16 | Issue 2 | Original Article | 105 | Copyright © February 2017
Fungal infection of the nails is an increasingly recognized disease in infants and children. However, it can be difficult to distinguish clinically from other nail dystrophies. In addition, many mi...
Read MoreNew Topical Therapeutic Options in the Management of Superficial Fungal Infections
October 2015 | Volume 14 | Issue 10 | Supplement Individual Articles | 35 | Copyright © October 2015
Dermatophyte infections of the skin and nails are common in the United States. These infections warrant treatment because they are symptomatic and progressive, and can predispose patients to superinfe...
Read MoreOnychomycosis Diagnosis and Management: Perspectives from a Joint Dermatology-Podiatry Roundtable
September 2015 | Volume 14 | Issue 9 | Original Article | 1016 | Copyright © September 2015
Onychomycosis prevalence is expected to rise as the population ages and the prevalence of diabetes, peripheral vascular disease, and other significant risk factors rise. Until recently, treatment opti...
Read MoreIn Vitro Nail Penetration of Tavaborole Topical Solution, 5%, Through Nail Polish on Ex Vivo Human Fingernails
July 2015 | Volume 14 | Issue 7 | Original Article | 675 | Copyright © July 2015
BACKGROUND: Onychomycosis is a common infection of the toenails that causes nail thickening and discoloration. The physical appearance of the infected nail can diminish self-image and negatively impac...
Read MoreOnchomycosis: An Overview
July 2013 | Volume 12 | Issue 7 | Supplement Individual Articles | 96 | Copyright © July 2013
Onychomycosis is a fungal infection of the nail unit, more common in toenails than in fingernails, and caused by a variety of fungi including dermatophytes, nondermatophyte molds, and Candida.Read More
CLINICAL TRIAL REVIEW
August 2012 | Volume 11 | Issue 8 | Features | 1012 | Copyright © August 2012
Clinical Trial Review is a JDD department designed to provide physicians with information on drugs and devices undergoing clinical testing. It is our goal to inform the reader of the status of select ...
Read MoreClinical Evaluation of Safety and Efficacy of a New Topical Treatment for Onychomycosis
October 2011 | Volume 10 | Issue 10 | Original Article | 1186 | Copyright © October 2011
Objective: This clinical study assessed the safety and efficacy of an investigational topical product for the treatment of onychomycosis (nail fungus). Method: A prospective, multi-center, single-arm...
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