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A Comparative Analysis of 8 Facial Cleansers Using Corneosurfametry Reveals Differentiated Irritation Potential

By July 20, 2026No Comments

How Mild Is Your Cleanser? New JDD Data on Facial Cleanser Tolerability 

This is a must-read article from JDD for dermatologists and dermatology healthcare professionals focused on sensitive skin care. Choosing the right facial cleanser is a routine decision in practice, but not all gentle cleansers behave the same way on skin. A new study in the Journal of Drugs in Dermatology compares Cetaphil® Gentle Skin Cleanser with seven other commercially available gentle cleansers using corneosurfametry, a technique designed to assess cleanser-induced irritation.

In this investigation, surface skin cells from volunteer participants were exposed to cleanser solutions and then evaluated with colorimetric analysis. The study found that Cetaphil Gentle Skin Cleanser showed a significantly higher colorimetric index of mildness than the comparator cleansers, suggesting a milder profile under the conditions tested. Photographic analysis of the tape strips supported those findings.
For clinicians counseling patients with sensitive skin, eczema-prone skin, or a history of cleanser irritation, this kind of comparative data may be useful when selecting a daily face wash as part of a tailored skin care regimen. While facial cleansers are often treated as interchangeable, this study reinforces that irritation potential can vary across products marketed as gentle.

If you are looking for practical evidence to guide cleanser recommendations in sensitive skin management, this JDD article offers a useful update worth reviewing. Read the full study to see how the authors assessed mildness and what the findings may mean for your patients.

Blog write-up assisted by AI