Combined Relabotulinum Toxin A frontalis modulation with NASHA™ gel skinboosters for the temples yields natural‑looking wrinkle softening and lasting skin quality gains beyond six months
A preliminary clinical series tested a combined, minimally invasive protocol pairing Relabotulinum Toxin A injections to modulate frontalis activity with monthly NASHA™ gel skinbooster injections into the temporal region. Early results suggest the regimen is well tolerated, delivers rapid frontalis smoothing (onset often within 24-48 hours) and produces progressive improvements in skin tone, hydration, elasticity and a subtle eyebrow tail lift that persist past six months.
Patient‑reported satisfaction and psychological benefits were noted, and the authors propose the effects reflect complementary mechanisms – neuromodulation to reduce dynamic forehead lines plus collagen‑stimulating volumization to restore temporal support and skin quality.
For the dermatologists, this approach offers a practical, synergistic option when both muscle hyperactivity and temporal volume/skin quality contribute to upper‑face aging. Individualize dosing and injection points based on anatomy and function, use blunt cannula technique for subcutaneous temporal skinbooster placement where appropriate, and counsel patients about the gradual, natural‑looking course and expected duration.
Read the full article to review dosing strategies, injection maps, safety observations and patient selection criteria before adopting this combined protocol.
J Drugs Dermatol. 2026;25(1). doi:10.36849/JDD.9621
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