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Private Insurance Coverage for Botulinum Toxin for Primary Axillary Hyperhidrosis: A Cross-Sectional Analysis

By December 23, 2025No Comments

Coverage clears the way: Most large private insurers pay for Botox and friends for axillary hyperhidrosis

In one of our January JDD articles, we reviewed public medical‑policy guidance from the largest private insurer in each US state to determine whether botulinum toxin is covered for primary axillary hyperhidrosis. For 40 states with available policies, every insurer explicitly listed axillary hyperhidrosis as an indication for medically necessary botulinum toxin after failure of topical or oral therapy, and prior authorization was universally required. Most policies covered multiple type‑A formulations (eg, onabotulinumtoxinA, daxibotulinumtoxinA, abobotulinumtoxinA, incobotulinumtoxinA) and the mean number of covered sessions per year was about 3.9. Despite broad coverage, patients still face substantial out‑of‑pocket costs driven by copays, deductibles and the need for repeat injections; the analysis was limited to each state’s largest private payer and did not include smaller insurers or public programs.

The practical takeaways are clear: botulinum toxin is generally recognized as medically necessary by major private payers, but secure prior authorization and counsel patients about likely cost burdens and expected retreatment intervals. Read the full article for the state‑by‑state policy table, sample prior‑authorization language, and tips to streamline approvals and discuss financial assistance options with patients.

J Drugs Dermatol. 2026;25(1). doi:10.36849/JDD.9398
Blog write-up assisted by AI