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Alopecia Universalis: Never Give Up?

By March 18, 2025No Comments
Journal of Drugs in Dermatology JDD about Alopecia Universalis: Never Give Up. Image of alopecia areata in pediatric patient.

JAK Inhibitors in Alopecia Areata: A Case for Persistence?

Oral Janus kinase inhibitors (JAKi) have emerged as a promising treatment for severe alopecia areata, with FDA-approved options now available. But what happens when initial therapy doesn’t deliver the expected results?

A new case report explores the long-term use of JAK inhibitors and what may influence treatment success in patients with refractory disease. The findings raise important considerations about treatment duration and intra-class switching—key factors that could impact clinical decision-making.

Could an adjusted approach to JAKi therapy improve patient outcomes?