Senior Resident Peer-to-Peer Case Studies openaccess articles

May 2018 | Volume 17 | Issue 5 | Editorials | 571 | Copyright © 2018

Elizabeth Robinson, Jennifer Aronica

GW School of Medicine and Health Sciences, Department of Dermatology

Abstract

The content of these case studies, ideal to review during peer study groups, was developed by Elizabeth Robinson, MD and Jennifer Aronica, MD under the guidance of dermatologist Adam Friedman, MD, FAAD, Associate Professor of Dermatology, Residency Program Director, Director of Translational Research, Department of Dermatology GW University

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For more practice Q&A and Board prep study tools—visit DermInReview.com.Case Studies authored by our educational partner GW School of Medicine and Health Sciences Dermatology Residency Program.1) Q1aQ1BQ1CA 40-year-old woman presented to clinic for evaluation of multiple “skin growths” on her face, hands and gums that had increased in number over the past 10 years. Her past medical history was remarkable for invasive ductal carcinoma of the left breast, multiple colon polyps, a benign thyroid nodule and uterine fibroids. Classic phenotypic features of this disease include all of the following features except:A. Lipomas

B. Macrocephaly

C. TrichoepitheliomasD. Sclerotic fibromasE. Hemangiomas2) A 65-year-old man presented with an asymptomatic, purulent ulcer on his neck increasing in size for the past four years. Review of systems was notable for a 30-pound weight loss in the past year. Physical exam showed this ulcer and posterior cervical lymphadenopathy. Chest computed tomography found scattered round nodules of varying sizes in both lungs. Oral therapy for this disease targets what factor?A. p53B. t(17;22)C. PatchedD. SmoothenedE. Cytotoxic T-lymphocyte antigen 43)Q3aQ3BA 38-year-old African American female presents for management of several pink papules growing on her elbows and groin. She also has multiple soft, skin-colored and hypopigmented blaschkolinear nodules with representative pathology shown here. Her daughter and granddaughter have similar skin findings as well as ectrodactyly. Which of the following is true regarding the disorder?A. The disease is inherited in an X-linked recessive fashion.B. This is caused by a mutation in the PORCN gene. C. The disorder progresses through four stages.D. This condition is associated with an immunodeficiency.E. Both B and D are correct.

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