Use of Isoquercetin in the Treatment of Prurigo Nodularis
November 2017 | Volume 16 | Issue 11 | Case Reports | 1156 | Copyright © November 2017
Christine M. Pennesi BS,a John Neely MD,b Ames G. Marks Jr. MD,b and S. Alison Basak MD MAb,c
aPenn State College of Medicine, Hershey, PA bPenn State Milton S. Hershey Medical Center, Hershey, PA cForefront Dermatology, St Louis, MO
Atopic dermatitis and prurigo nodularis result from complex interactions between the skin, the immune system, and the external environment. The pruritus associated with these conditions greatly impacts patients’ quality of life and lacks uniformly effective treatment. A 57-year-old patient presented with severe atopic dermatitis and subsequent prurigo nodularis refractory to numerous standard therapies. The supplement isoquercetin was initiated and he noted significant, sustained reduction in his pruritus after only four weeks. Isoquercetin is a glycoside derivative with antihistamine properties of quercetin, a natural polyphenol flavonoid found in many plants. It may offer itch relief in patients who have failed more conventional therapies.
J Drugs Dermatol. 2017;16(11):1156-1158.
Keywords: Case Report
