Issue Archive
August 2010 | Volume 9 | Issue 8
Editorials
Letter to the Editor
Minocycline is Effective and Cosmetically Preferred to Clofazimine by Leprosy Patients in New York...
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Original Articles
Approaching Psoriasis Differently: Patient-Physician Relationships, Patient Education and Choosing the Right Topical Vehicle
Psoriasis is a common, frustrating problem for dermatologists and patients. Long-held notions about the need to use thick, greasy corticosteroid ointments for psoriasis contributed to frustration for...
Read MoreScalp Psoriasis: An Overview of the Disease and Available Therapies
The scalp is one of the regions of the body most commonly affected by psoriatic lesions. While the head represents only 10 percent of the body’s surface area, the consequences of scalp psorias...
Read MoreStatins in Skin: Research and Rediscovery, From Psoriasis to Sclerosis
Statins, initially developed as antimicrobials, are primarily considered cholesterol-lowering agents. Recently, researchers discovered anti-inflammatory properties of statins. Studies on the effects o...
Read MoreLong-term Safety and Efficacy of Etanercept in Patients With Psoriasis: An Open‑label Study
Background: In two previous phase 3 studies, up to 60 weeks of etanercept therapy significantly improved the symptoms of psoriasis and was well tolerated. Objective: To evaluate the long-term safety...
Read MoreTreatment Patterns and Perceptions of Treatment Attributes, Satisfaction and Effectiveness Among Patients With Psoriasis
Psoriasis is a chronic autoimmune condition that affects over 7 million Americans, approximately 1–3 percent of the population. Although there are a number of treatment options currently avail...
Read MoreProspective New Biologic Therapies for Psoriasis and Psoriatic Arthritis
Psoriasis and psoriatic arthritis are immune-mediated, chronic, inflammatory diseases that place a heavy burden on the lifestyle of patients affected. Current understanding of the pathophysiology of ...
Read MoreEfficacy of 15% Azelaic Acid in Psoriasis Vulgaris: A Randomized, Controlled Clinical Trial
Background: Psoriasis is a common disorder affecting 1–3 percent of the general global population. Many therapeutic modalities have been suggested for treatment of this condition, but still th...
Read MoreShort- and Long-term Safety Assessment of a Two-compound Ointment Containing Calcipotriene/Betamethasone Dipropionate (Taclonex®/Daivobet®/Dovobet® Ointment): Hypothalamic-Pituitary-Adrenal Axis Function in Patients with Psoriasis Vulgaris
The two-compound ointment (Taclonex®/Daivobet®/Dovobet® ointment) combining calcipotriene 50 μg/g and betamethasone 0.5 mg/g (as dipropionate) is very effective in the treatment of psor...
Read MoreUse of Biologic Agents in Pediatric Psoriasis
Psoriasis affects approximately 2 percent of the population. Approximately 30–45 percent of those affected first experience symptoms during childhood or adolescence. Although biologics have pr...
Read MoreThe Usefulness of Narrowband UV B as a Monotherapy for the Treatment of Chronic Plaque Psoriasis
Objective: To assess the efficacy and safety of narrowband ultraviolet B (UVB) phototherapy in dark-skinned Saudi patients with chronic plaque psoriasis. Patients and Methods: This prospective study...
Read MoreAn Evidence-based Review of the Efficacy of Topical Antihistamines in the Relief of Pruritus
Objective: To critically review the body of clinical trials refuting or supporting the efficacy of topical antihistamines in the relief of pruritus. Design: Review of PubMed from January 1950 through...
Read MoreIrritation Potential of Tretinoin Gel Microsphere Pump Versus Adapalene Plus Benzoyl Peroxide Gel
This single-center, investigator-blinded, randomized, split-face, phase 4 study compared the irritation potential of tretinoin gel microsphere (TGM) 0.04% in a pump dispenser with adapalene 0.1% plus ...
Read MoreNews, Views & Reviews
The New Melanoma Staging System: What the Clinician Should Know...
Read MorePipeline previews
Pipeline Previews brings to you information on the newest drugs and medical products as they become available to the dermatological community. This department may include additional information from t...
Read MoreClinical Trial Review
Clinical Trial Review is a JDD department designed to provide physicians with information on drugs undergoing clinical testing. It is our goal to inform the reader of the status of select drug trials ...
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Case Reports
Progressive Multifocal Leukoencephalopathy in Two Psoriasis Patients Treated With Efalizumab
Progressive multifocal leukoencephalopathy (PML) is a rare neurological disorder that occurs almost exclusively in immunocompromised individuals by reactivation of the John Cunningham virus (JC virus...
Read MoreA Case of Bupropion-induced Stevens-Johnson Syndrome With Acute Psoriatic Exacerbation
Bupropion is a very popular medication prescribed to millions of patients globally for depression (Wellbutrin®, GlaxoSmithKline, Research Triangle Park, NC) as well as an aid in smoking cessation ...
Read MoreDevelopment of Hodgkin’s Lymphoma Under Bexarotene Treatment for Sézary Syndrome and Review of the Literature
There are several reports of patients who developed extracutaneous lymphoma after they started bexarotene treatment. The authors report a case in which the initiation of bexarotene therapy for Séz...
Read MoreSix Patients With Early-Stage Cutaneous T-cell Lymphoma Successfully Treated With Topical 5-fluorouracil
Topical 5-fluorouracil (5-FU) has been used in the treatment of various benign and malignant tumors of the skin, but only few address its therapeutic value on cutaneoues T-cell lymphoma. (CTCL). The ...
Read MoreLocalized Argyria Secondary to Acupuncture Mimicking Blue Nevus
The typical clinical manifestation of localized cutaneous argyria is a blue-grayish asymptomatic macule, which may be caused by occupational exposure, topical treatment, dental amalgams and alternativ...
Read MoreDevelopment of Subacute Cutaneous Lupus Erythematosus Associated With the Use of Imiquimod to Treat Actinic Keratoses
The immunomodulating drug imiquimod is approved by the U.S. Food and Drug Administration (FDA) to treat actinic keratoses, nonfacial superficial basal cell carcinomas and genital warts. This drug elic...
Read MoreCutaneous Fixed Drug Eruption to Fluconazole
Fixed drug eruption (FDE) is an uncommon medication-induced cutaneous reaction. A case of fluconazole-induced FDE is described. A 64-year-old woman presented with eight ovoid hyperpigmented patches o...
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Supplements
Scientific Proceedings From Select Sessions at the2010 Orlando Dermatology Aesthetic & Clinical (ODAC) Conference–Part II
Scalp Psoriasis, How and When to Use Biologics in Psoriasis, Enhancing the Eyes: Use of Minimally Invasive Techniques for Periorbital Rejuvenation, and Facial Shaping: Beyond Lines and Folds With Fill...
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