Issue Archive
October 2008 | Volume 7 | Issue 10
Original Articles
Efficacy of Adalimumab for Plaque Psoriasis: Experience with 28 Patients
Psoriasis is a common, chronic inflammatory skin disease with arthritis that may occur in a percentage of patients that varies between 5% and 42%. Many systemic agents as cyclosporine, methotrexate, ...
Read MoreEtanercept in the Treatment of Palmoplantar Pustulosis
Introduction: Palmoplantar pustulosis (PPP) is a chronic, recurrent and difficult to treat skin condition characterized by the presence of pustules, erythema, and hyperkeratosis on palms and soles. ...
Read MoreTreatment of Moderate to Severe Plaque Psoriasis With Concomitant Efalizumab and Narrow-Band Ultraviolet B Phototherapy
Background: Efalizumab therapy and narrow-band ultraviolet B (NB-UVB) phototherapy have different mechanisms of action; com- bined therapy may be more effective than either treatment alone in treati...
Read MoreTopical Tetracycline in the Treatment of Acne Vulgaris
Background: Topical tetracycline was the first topical antibiotic approved for the treatment of acne, its use has been limited because of the skin penetration problems of the active ingredient.
...
Read MoreRelapse of Acne Following Isotretinoin Treatment: A Retrospective Study of 405 Patients
Background: Isotretinoin is the most effective systemic treatment option for patients with nodulocystic acne or acne vulgaris who have failed a treatment with systemic antibiotics.
Methods: We...
Read MoreExpression of CD70 and the TH17 Transcription Factor RORγT in Human Contact Dermatitis
Contact sensitizers are a major cause of inflammatory skin disease and as topical immunomodulators also have the potential for treat- ing cancer, viral diseases and certain autoimmune disorders. In ...
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Features
Case Reports
Verrucous Linear (Segmental) Psoriasis of the Right Leg Responding to Radiation Therapy
Verrucous linear segmental psoriasis (VLSP) is invariably recalcitrant to treatment. It is a distinct variant of psoriasis that frequently is considered a form of a verrucous linear, epidermal nevus...
Read MorePsoriasis and Psoriatic Arthritis in a Patient with HIV: Response to Mycophenolate Mofetil Treatment
A case of psoriasis and psoriatic arthritis in a 38-year-old white male patient infected with human immunodefi ciency virus (HIV) treat- ed safely and effectively with mycophenolate mofetil (M...
Read MorePustular Psoriasis Following Treatment of Rheumatoid Arthritis With TNF-alpha Inhibitors
Pityriasis Rubra Pilaris with Epidermolytic Hyperkeratosis
Refractory Dissecting Cellulitis of the Scalp Treated With Adalimumab
Dissecting cellulitis of the scalp (DCS) is a suppurative, neutrophillic dermatosis. Therapies typically provide short-term improvement and include antibiotics, prednisone, and isotretinoin, as well...
Read MoreSevere Erythroderma in a Patient Under Intermittent Therapy with Efalizumab
The author presents the case of a 27-year-old man who suffered 2 episodes of erythroderma while on therapy with efalizumab for psoriasis. The fi rst episode, occurred 2 weeks after the fi...
Read MoreEtanercept in Therapy Multiresistant Overlapping Pityriasis Lichenoides
Introduction: Pityriasis lichenoides (PL) exhibits a protean clinical presentation, particularly in its overlapping form (OPL) combin- ing aspects of the acute and chronic types. Some patients are d...
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