Issue Archive
December 2020 | Volume 19 | Issue 12
Editorials
Predicting Secukinumab Fast-Responder Profile in Psoriatic Patients: Advanced Application of Artificial-Neural-Networks (ANNs)
Background: Drug resistance to biologics in psoriasis therapy can occur – it may be acquired during a treatment or else present itself from the beginning. To date, no biomarkers are known that m...
Read MoreTeledermatology: Improving Access or Widening Healthcare Disparities?
Teledermatology, the form of telemedicine directed toward dermatology patients, is one of the earliest technological innovations that advanced remote medical care. Developed in 1995, teledermatology w...
Read MoreOptimizing the Trial Design for a Comparative Effectiveness Study of Spironolactone versus Oral Antibiotics for Women With Acne: A Delphi Consensus Panel
For women with acne, their acne often persists into adulthood, with over 50% of women reporting acne between 20–29 years of age and over 35% of women reporting acne between 30–39 years of ...
Read MoreHispanic/Latinos and Skincare: Disparities in Product Development, Marketing, and Toxicity
“Hispanic” and “Latino” (also known as Mestizo) describe a diverse racial and ethnic group, with a range of cultures, languages, and biological ancestry. It includes individual...
Read MoreEffectiveness of Pediatric Teledermatology
Initial studies of teledermatology in pediatric populations indicated that many of the problems experienced in adult virtual visits were even more apparent when treating children. Specifically, it was...
Read MoreAnalysis of Skin Color on the American Academy of Dermatology Public Education Website
Access to health information online has resulted in increased internet use to !nd medical education resources.1,2 The United States (US) population is comprised of 60.1% Whites, 18.5% Hispanics or Lat...
Read MoreUse of Topical Timolol Maleate as Re-Epithelialization Agent for Treatment of Recalcitrant Wounds of Varying Etiologies
Background: Chronic wounds remain a challenge for the clinician and healthcare system. It is therefore vital for additional therapies that target steps involved in wound recalcitrance. Recently, topic...
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Original Articles
Clinical Evaluation of a Nature-Based Bakuchiol Anti-Aging Moisturizer for Sensitive Skin
Background: Patients with sensitive skin find topical retinoid use for anti-aging purposes challenging due to irritation. Bakuchiol, a meroterpene from the Psoralea corylifolia seed, has retinol funct...
Read MoreApremilast with Add-On Calcipotriene/Betamethasone Dipropionate for Treating Moderate to Severe Plaque Psoriasis
Background: About 20% of patients taking apremilast alone obtain PASI 75 by week 8. This single-center, pilot study aimed to determine whether add-on topical therapy with calcipotriene/betamethasone d...
Read MoreTolerability of Six Months Indirect Cold (Physical) Plasma Treatment of the Scalp for Hair Loss
Androgenetic alopecia (AGA) is a chronic form of hair loss. Cold atmospheric (physical) plasma (CAP) is partly ionized gas with various widely researched effects on living tissues. CAP is an emerging ...
Read MoreOxytocin Levels Inversely Correlate With Skin Age Score and Solar Damage
Background: Studies have shown oxytocin (OT) and its carrier protein neurophysin 1 are found in the epidermis. The oxytocin receptor, which is found on human fibroblasts has been shown, when activated...
Read MoreAn Observational Study of the Application of a Topical Cannabinoid Gel on Sensitive Dry Skin
Atopic dermatitis (AD) is a chronic skin disorder characterized by pruritus, erythema and excoriation. While AD has a multifactorial etiology, neuro-signaling pathways are now recognized to play an es...
Read MoreRacial Differences in Treatment Preferences of Acne Vulgaris: A Cross-Sectional Study
Cultural and social constructs may influence a patient’s understanding of their acne vulgaris affecting treatment preferences and valuation. Understanding these differences can better equip heal...
Read MoreTime Intervals Until the First Return Office Visit After New Medications
Introduction: Poor patient adherence to medications is common in dermatology and can result in negative health outcomes. A short interval until the first return office visit after starting a medicatio...
Read MoreThe Role of Platelet Homeostasis in a Novel Topical PRP Formulation
Background: Topical platelet-rich plasma (PRP) must demonstrate stability to insure biologic activity in aesthetic medicine.
Objective: The objective of this research was to evaluate the role of...
Read MoreAssessing Patients’ Satisfaction With Hydrogen Peroxide Topical Solution, 40% for Treatment of Raised Seborrheic Keratoses
Objectives: Assess participants’ satisfaction following treatment with a proprietary hydrogen peroxide topical solution 40%, w/w (HP40) for raised seborrheic keratoses (SKs).
Methods: In t...
Read MoreUveitis for Dermatologists: A Review
Certain dermatologic conditions and drugs used for their treatment are associated with uveitis, a vision-threatening group of inflammatory eye diseases. Dermatologists may therefore be the first healt...
Read MoreClinical Benefits of Circadian-based Antioxidant Protection and Repair
Skin activities follow endogenous circadian rhythms resulting in differences between daytime and nighttime properties. To address the variations in skin needs, a novel circadian-based dual serum syste...
Read MoreEvaluation of Clinical Properties and Treatment Responses of Infantile Hemangioma
Background: Infantile hemangiomas are the most common vascular tumors in childhood. Although spontaneous regression is common; several infantile hemangioma patients need treatment due to possible morb...
Read MoreImmediate Use After Reconstitution of a Biostimulatory Poly-L-Lactic Acid Injectable Implant
Background: Poly-L-lactic acid (PLLA) is a biodegradable, synthetic polymer that stimulates collagen production and can improve skin quality, volume, and thickness. The current reconstitution procedur...
Read MoreMetformin as Adjunctive Therapy for Pediatric Patients With Hidradenitis Suppurativa
Background: Hidradenitis suppurativa (HS) is a chronic inflammatory disorder seen in adolescents and adults characterized by abscesses, sinus tracts and scarring, typically affecting intertriginous sk...
Read MoreNovel Recombinant Tropoelastin Implants Restore Skin Extracellular Matrix
Background: Elastin is an essential component of the dermis, providing skin with elasticity and integrity. Elastin and other dermal components are gradually lost through aging, sun damage, and followi...
Read MoreCorrection of Skin Depressions of the Hands and Décolletage With VYC-17.5L: A Prospective, Single-center Study
Background: Few studies have assessed the use of hyaluronic acid (HA) fillers for rejuvenating the hands and décolletage. VYC-17.5L is an HA filler with physical properties that may be well sui...
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Case Reports
Update on Biotin Therapy in Dermatology: Time for a Change
Biotin (vitamin B7 or H) is found in milk, nuts, egg yolks, cereals, supplements, synthesized by intestinal bacteria, and is required for gluconeogenesis, fatty acid synthesis and amino acid catabolis...
Read MoreThe Pinch Stitch: A Pearl for Suturing Wounds Under Tension
Closing defects under tension in areas such as the scalp and back may be challenging during dermatologic surgery. Different techniques have been advocated to ease the placement of the first deep sutur...
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