Issue Archive
March 2006 | Volume 5 | Issue 3
Original Articles
Crusted Scabies: A Clinical Review
Crusted scabies, a rare variant of classical scabies, is a highly contagious condition in which the skin is infected with thousands to millions of mites. It can be defined as a generalized severe sca...
Read MoreImatinib Mesylate and Dermatology Part 2: A Review of the Cutaneous Side Effects of Imatinib Mesylate
Cutaneous reactions to imatinib are common and occur in 9.5% to 69% of patients depending on the series reported. Maculopapular eruptions, erythematous eruptions, edema, and periorbital edema are the...
Read MoreCombination Topical Therapy for the Treatment of Psoriasis
Dermatological research continues to move toward the goal of developing an effective psoriasis treatment that would rapidly clear lesions and provide long-term freedom from visible signs and symptoms...
Read MoreA Multicenter, Randomized, Vehicle-Controlled Clinical Study to Examine the Efficacy and Safety of MAS063DP (Atopiclairâ„¢) in the Management of Mild to Moderate Atopic Dermatitis in Adults
Background: MAS063DP cream has received marketing authorization in the US and the European Union for symptom relief of atopic dermatitis (eczema) and contact dermatitis.
Design: A multicente...
Read MoreEsophagitis due to Tetracycline and its Derivatives in Dermatology Patients
Medication induced esophagitis (MIE) has been reported in dermatology patients taking tetracycline antibiotics. The symptoms of esophagitis, preventable with proper instruction, can create morbidity ...
Read MoreSustained Efficacy and Safety of Infliximab in Psoriasis: A Retrospective Study of 73 Patients
Background: Infliximab inhibits T-cell activation by binding tumor necrosis factor-? (TNF-?). This medication is widely used in the US for treatment of psoriasis as an off-label indication. The durab...
Read MoreTazarotene versus Tazarotene plus Clindamycin/Benzoyl Peroxide in the Treatment of Acne Vulgaris: A Multicenter, Double-Blind, Randomized, Parallel-Group Trial
Topical retinoids offer highly effective treatment for both inflammatory and non-inflammatory acne, with tazarotene demonstrating greater efficacy than other topical retinoids. A multicenter, double-...
Read MoreEfficacy and Safety of the Topical Sensitizer Squaric Acid Dibutyl Ester in Alopecia Areata and Factors Influencing the Outcome
Background: Immunotherapy with sqauric acid dibutyl ester (SADBE) is a well-accepted therapy for alopecia areata.
Objective: To study efficacy, safety, and factors influencing the outcome in ...
Read MoreGel Vehicles Are Not Inherently More Irritating than Creams
Background: It has been thought that topical gels are inherently more irritating than topical creams. Nevertheless, the irritancies of topical products are potentially quite variable, and a priori as...
Read MoreCutaneous Effects of Sirolimus in Renal Transplant Recipients
Cancer is a major cause of death in immunosuppressed transplant patients. Therefore, sirolimus is frequently used in these patients for its immunosuppressive and antineoplastic properties. However, a...
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Features
Case Reports
Primary Cutaneous Nodular Amyloidosis in a Patient with Sjögren’s Syndrome7
A 71-year-old woman with a history of Sjögren’s syndrome presented for evaluation of a waxy nodule present on the scalp for 6 months. Histopathologic examination revealed deposition of homo...
Read MoreA Case of an Adverse Reaction to Topical 5-Fluorouracil in Irradiated Skin
A 73-year-old Caucasian male was treated in the dermatology clinic for squamous cell carcinoma (SCC) of the scalp by Mohs micrographic surgery. The patient subsequently received radiation therapy bec...
Read MoreSerum Sickness-like Reaction to Pamabrom
Pamabron is a common over-the-counter diuretic used for relief of menstrual-associated symptoms. An urticarial eruption, with systemic complaints consistent with a serum sickness-like reaction, attri...
Read MoreAmantadine-Induced Livedo Reticularis: A Report of Two Cases
In the last several years, amantadine has been increasingly prescribed for akinesia in Parkinson’s disease and to combat fatigue associated with multiple sclerosis. Amantadine is a well-known ...
Read MoreThe Treatment of Progressive Pigmented Purpura with Ascorbic Acid and a Bioflavonoid Rutoside
Progressive pigmented purpura (PPP) is a group of dermatoses that are benign and usually self-limited. However, they may persist for months or years with frequent recurrences. Numerous treatments hav...
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