Issue Archive
March 2005 | Volume 4 | Issue 2
Original Articles
Dioxin Toxicity and Chloracne in the Ukraine
Dioxin toxicity can lead to severe cutaneous and systemic disease. The poisoning of Ukrainian President Viktor Yushchenko dramatically illustrates the damage dioxin can inflict. The hallmark of dioxi...
Read MoreTazarotene Cream versus Adapalene Cream in the Treatment of Facial Acne Vulgaris: A Multicenter, Double-Blind, Randomized, Parallel-Group Study
A multicenter, double-blind, randomized, parallel-group trial compared tazarotene 0.1% cream with adapalene 0.1% cream, once daily for 12 weeks, in 173 patients with facial acne vulgaris. Tazarotene ...
Read MoreTreatment of Actinic Keratoses with Sequential Combination of 5-Fluorouracil and Photodynamic Therapy
Actinic keratoses (AKs) are traditionally treated with cryotherapy, curettage, and 5-fluorouracil (5-FU, Efudex®, ICN Pharmaceuticals, Inc.), all of which are associated with adverse effects. Alth...
Read MoreClinical Experience Results with Clindamycin 1% Benzoyl Peroxide 5% Gel (Duac®) as Monotherapy and in Combination
This article will examine various clinical experiences with acne patients successfully treated with topical clindamycin 1% benzoyl peroxide 5% gel (Duac®) alone and in combination with other acne ...
Read MorePrescribing Patterns for Topical Retinoids within NAMCS Data
Objective: Fears of potentially costly use of topical retinoids for cosmetic treatment of photodamaged skin have resulted in many managed care organizations placing prior authorization requirements o...
Read MoreEnhanced Full-Face Skin Rejuvenation Using Synchronous Intense Pulsed Optical and Conducted Bipolar Radiofrequency Energy (ELOS): Introducing Selective Radiophotothermolysis
Background: The authors previously reported their experience achieving non-ablative skin enhancement with serial, full-face, intense pulsed light treatments in a large series of patients. A new metho...
Read MoreReview of Cyclosporine Immunosuppressive Safety Data in Dermatology Patients after two Decades of Use
Cyclosporine is an immunosuppressive agent that has been shown to be effective in the treatment of psoriasis. However, its serious side effects in transplant patients have hindered many dermatologist...
Read MoreColchicine for Dermatologic Diseases
The authors review all aspects related to colchicine from its pharmacology to its usage in several skin diseases...
Read MoreDrugs Used in the Treatment of Pediculosis
Pediculosis is the result of infestation by one of two families of sucking lice. The Pediculidae include the agents of head and body lice. Pubic lice belong to the family Pthiridae. Pediculus humanus...
Read MoreTen Commandments for Minimal Pain during Aministration of Local Anesthetics
Local anesthetic agents are administered before many ambulatory cutaneous operations. The injection of the local anesthetic agent is often the only painful aspect of the procedure. There are various ...
Read More
Features
FOCUS ON: Biologics that Affect Therapeutic Agents in Dermatology
Tumor necrosis factor (TNF)-α is one of the oldest known cytokines in human physiology. It is involved in both normal and pathologic states. Virtually every cell and organ in the body are affected...
Read MoreWASHINGTON WHISPERS
PIPELINE PREVIEWS
CLINICAL TRIAL REVIEWS
Case Reports
Acute Generalized Lichen Planus Treated with Weekly Betamethasone 5-mg Mini-Pulse Therapy
A 54-year-old male presented with a sudden generalized eruption of itchy violaceous papules, annular plaques, superficial vesicles, and erosions involving his trunk, limbs, oral cavity, and genitalia...
Read MorePsoriasis Exacerbated by Interferon-alpha in a Patient with Chronic Myeloid Leukemia
Interferon-alpha can exacerbate existing psoriasis and induce de novo psoriasis and psoriatic arthritits. The exact underlying mechanism is not very well understood. It is not a contraindication to t...
Read MoreCo-Existence of Lichen Planus and Sarcoidosis
We present a 53-year-old patient with respiratory sarcoidosis who subsequently developed cutaneous lichen planus (LP). Biopsy of the skin lesions showed typical LP with no evidence of sarcoid granulo...
Read MoreRhabdomyolysis Associated with Quinacrine Therapy in a Patient with Chronic Cutaneous Lupus Erythematosus
We describe a patient who developed rhabdomyolysis 6 weeks after starting combination therapy with hydroxychloroquine and quinacrine for the treatment of chronic cutaneous lupus erythematosus (CCLE)....
Read MoreTazarotene Cream (0.1%) in Combination with Betamethasone
A combination of multiple agents is often required to achieve treatment success for plaque-type psoriasis. We report a case series of 10 patients that were treated with betamethasone valerate foam (0...
Read MoreScrotal Ulceration as a Consequence of All-Trans-Retinoic Acid (ATRA) for the Treatment of Acute Promyelocytic Leukemia
Induction therapy with all-trans-retinoic acid (ATRA), an oral vitamin A derivative, has been shown to improve the short and long-term outcome of patients with acute promyelocytic leukemia (APML). Co...
Read More
