Treatment of Sebaceous Hyperplasia With a Novel 1,720-nm Laser

November 2012 | Volume 11 | Issue 11 | Original Article | 1323 | Copyright © November 2012


Douglas Winstanley DO, Travis Blalock MD, Nancy Houghton BS, and E. Victor Ross MD

Scripps Clinic Laser and Cosmetic Dermatology, San Diego, CA

superficial portions of the gland and sparing of the surrounding skin. The one biopsy shows that although selectivity is possible with this wavelength, the relatively shallow optical penetration depth prevents complete destruction of the deeper portions of some larger lesions. However, those deeper portions are less visible at the surface, and presumably mild fibrosis over the surviving portion of the lesion obscures the conspicuous yellow nature of the lesion.
This small pilot study supports the utility and safety of this wavelength in the treatment of sebaceous hyperplasia. Larger studies and broader applications of this wavelength should be undertaken.

ACKNOWLEDGMENTS

The favor of the loan of the device used in this study was provided by Del Mar Technologies, Inc, Del Mar, CA.

DISCLOSURES

Dr. Blalock and Ms. Houghton have no conflicts of interest. Dr. Winstanley is currently serving as a medical officer in the U.S. Navy. The views expressed in this article are those of the authors and do not reflect the official policy or position of the Department of the Navy, Department of Defense, or the U.S. Government.

REFERENCES

  1. Aghassi D, González E, Anderson RR, Rajadhyaksha M, González S. Elucidating the pulsed-dye laser treatment of sebaceous hyperplasia in vivo with real-time confocal scanning laser microscopy. J Am Acad Dermatol. 2000;43(1 Pt 1):49-53.
  2. No D, McClaren M, Chotzen V, Kilmer SL. Sebaceous hyperplasia treated with a 1450-nm diode laser. Dermatol Surg. 2004;30(3):382-384.
  3. Horio T, Horio O, Miyauchi-Hashimoto H, Ohnuki M, Isei T. Photodynamic therapy of sebaceous hyperplasia with topical 5-aminolaevulinic acid and slide projector. Br J Dermatol. 2003;148(6):1274-1276.
  4. Bader RS, Scarborough DA. Surgical pearl: intralesional electrodesiccation of sebaceous hyperplasia. J Am Acad Dermatol. 2000;42(1 Pt 1):127-128.
  5. McDonald SK, Goh MS, Chong AH. Successful treatment of cyclosporineinduced sebaceous hyperplasia with oral isotretinoin in two renal transplant recipients. Australas J Dermatol. 2011;52(3):227-230.
  6. Yu C, Shahsavari M, Stevens G, Liskanich R, Horowitz D. Isotretinoin as monotherapy for sebaceous hyperplasia.J Drugs Dermatol.2010;9(6):699-701.
  7. Wanner M, Avram M, Gagnon D, et al. Effects of non-invasive, 1,210 nm laser exposure on adipose tissue: results of a human pilot study. Lasers Surg Med. 2009;41(6):401-407.
  8. Sakamoto FH, Doukas AG, Farinelli WA, et al. Selective photothermolysis to target sebaceous glands: theoretical estimation of parameters and preliminary results using a free electron laser. Lasers Surg Med. 2012;44(2):175-183

AUTHOR CORRESPONDENCE

Douglas Winstanley DOdwinst2@yahoo.com
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