Treatment of Schamberg’s Disease with Advanced Fluorescence Technology

April 2012 | Volume 11 | Issue 4 | Case Reports | 528 | Copyright © April 2012


Danielle A Manolakos DO MPH,a Jonathan Weiss MD,d Brad Glick DO MPH,aKathleen D Weiss BA,b Eduardo Weiss MD FAAD c, d

a Wellington Regional Medical Center/Lake Erie College of Osteopathic Medicine, Wellington, FL b University of Miami Miller School of Medicine, Miami, FL c Hollywood Dermatology and Cosmetic Specialists, Hollywood, FL d University of Miami Miller School of Medicine, Department of Dermatology and Cutaneous Surgery, Miami, FL

table 1
Schamberg's disease can be difficult to treat because of the lack of reliable therapies and the potential systemic side effects of oral medications. We describe a therapeutic approach to locally treat and improve the cosmetic appearance of patients with Schamberg's disease. In addition, this method avoids the possible side effects of systemic therapies. While clinical studies should be performed on larger patient populations, our experience has demonstrated that 570 nm AFT handpiece should be considered a viable and safe option in the treatment of Schamberg's disease. Our experience with this method has been limited to patients with clinically stable eruptions; however, the use of AFT therapy in combination with other agents such as pentoxifylline presents a prospective intervention for future study on patients with active disease.

DISCLOSURES

The authors have no relevant conflicts of interest to disclose.

REFERENCES

  1. Piette W. Purpura. Mechansims and Differential Diagnosis. In: Bolognia JL, Jorizzo JL, Rapini RP, editors. Dermatology. 2nd Edition. Spain: Elsevier; 2008:326-328.
  2. Kano Y, Hirayama K, Orihara M, Shiohara T. Successful treatment of Schamberg's disease with pentoxifylline. J Am Acad Dermatol. 1997;36(5 Pt 2):827-830.
  3. Tamaki K, Yasaka N, Osada A, Shibagaki N, Furue M. Successful treatment of pigmented purpuric dermatosis with griseofulvin.Br J Dermatol. 1995;132:159-160Lkj.
  4. Seckin D, Yazici Z, Senol A, Demircay Z. A case of Schamberg's disease responding dramatically to PUVA treatment. Photodermatol Photoimmunol Photomed. 2008;24(2):95-96.
  5. Lasocki AL, Kelly RI. Narrowband UVB therapy as an effective treatment for Schamberg's disease. Australas J Dermatol. 2008;49(1):16-18.
  6. Reinhold U, Seiter S, Urgurel S, Tilgen W. Treatment of progressive pigmented purpura with oral bioflavinoids and ascorbic acid: an open pilot study in 3 patients.J Am Acad Dermatol. 1999;41:207-208.
  7. Geller M. Benefit of colchicine in the treatment of Schamberg's disease. Ann Allergy Asthma Immunol. 2000;85(3):246.
  8. Sardana K, Sarkar R, Sehgal VN. Pigmented purpuric dermatoses: an overview. Int J Dermatol. 2004;43(7):482-488.
  9. Babilas P, Schremi S, SzeimiesRM, Landthaler M. Intense pulsed light (IPL): a review. Lasers Surg Med.2010;42(2):93-104.

ADDRESS FOR CORRESPONDENCE

Eduardo Weiss MD FAAD3850 Hollywood Boulevard, Suite 201Hollywood, FL 33021Phone: (954) 961-1200Fax: (954) 963-0378Email: sEWeiss1401@aol.com
Close Menu