Treatment of Recurrent Herpes Labialis

September 2014 | Volume 13 | Issue 9 | Features | 1016 | Copyright © September 2014


Deborah S. Sarnoff MD FAAD FACP

  1. Spruance SL, Rea TL, Thoming C, et al. Penciclovir cream for the treatment of herpes simplex labialis. A randomized, multicenter, double-blind, placebo-controlled trial. Topical Penciclovir Collaborative Study Group. JAMA 277(17):1374-9 (1997 May).
  2. Boon R, Goodman JJ, Martinez J, et al. Penciclovir cream for the treatment of sunlight-induced herpes simplex labialis: a randomized, double-blind, placebo-controlled trial. Penciclovir Cream Herpes Labialis Study Group. ClinTher 22(1):76-90 (2000 Sep).
  3. Evans TG, Bernstein DI, Raborn GW, et al. Double-blind, randomized, placebo-controlled study of topical 5% acyclovir-1% hydrocortisone cream (ME-609) for treatment of UV radiation-induced herpes labialis. Antimicrob Agents Chemother 46(6):1870-4 (2002 Jun).
  4. Downing C, Moayyad J, Tamirisa A, Tyring S. Acyclovir Lauriad: a muco-adhesive buccal tablet for the treatment of recurrent herpes labilias. Expert Rev Anti Infect Ther. 2014 Mar; 12(3):283-7.
  5. Karon A. Buccal acyclovir delays recurrence of herpes labialis. SkinandAllergy news.com 2014 June.
  6. Raborn GW, McGaw WT, Grace M, et al. Oral acyclovir and herpes labialis: a randomized, double-blind, placebo-controlled study. J Am Dent Assoc 115(1):38-42 (1987 Jul).
  7. Spruance SL, Stewart JC, Rowe NH, et al. Treatment of recurrent herpes simplex labialis with oral acyclovir. J Infect Dis 161(2):185-90 (1990 Feb).
  8. Spruance SL, Jones TM, Blatter MM, et al. High-dose, shortduration, early valacyclovir therapy for episodic treatment of cold sores: results of two randomized, placebo-controlled, multicenter studies. Antimicrob Agents Chemother 47(3):1072-80 (2003 Mar).
  9. Gilbert SC. Suppressive therapy versus episodic therapy with oral valacyclovir for recurrent herpes labialis: efficacy and tolerability in an open-label, crossover study. J Drugs Dermatol 6(4):400-5 (2007 Apr).
  10. Spruance SL, Bodsworth N, Resnick H, et al. Single-dose, patientinitiatedfamciclovir: a randomized, double-blind, placebo-controlled trial for episodic treatment of herpes labialis. J Am Acad Dermatol 55(1):47-53 (2006 Jul).
  11. Hull C, McKeough M, Sebastian K, et al. Valacyclovir and topical clobetasol gel for the episodic treatment of herpes labialis: a patientinitiated, double-blind, placebo-controlled pilot trial. J Eur Acad Dermatol Venereol 23(3):263-7 (2009 Mar).
  12. St. Pierre, SA, Bartlett BL, Schlosser BJ, Practical management measures for patients with recurrent herpes. Skin Therapy Lett. 2009 Nov-Dec;14(8):1-3.

AUTHOR CORRESPONDENCE

Deborah S. Sarnoff MD FAAD FACPAndrew.Sarnoff@gmail.com