Treatment of Arsenic-Induced Bowen’s Disease With Topical 5-Fluorouracil

May 2019 | Volume 18 | Issue 5 | Case Reports | 477 | Copyright © May 2019


Brendon Verhave BS,a Matthew Goldberg MD,b Peter Hashim MD,b Jacob Levitt MDb

aSUNY Upstate Medical University, Syracuse, NY bMount Sinai Health Systems, New York, NY

REFERENCES

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  3. Son, S. B., Song, H. J., Son, S. W. (2008). Successful treatment of palmoplantar arsenical keratosis with a combination of keratolytics and low-dose acitretin. Clin Exp Dermatol. 2008;33(2):202-204.
  4. Haque, R., Mazumder, D. N., Samanta, S., et al. Arsenic in Drinking Water and Skin Lesions: Dose-Response Data from West Bengal, India. Epidemiology. 2003;14(2):174-182.
  5. Khandpur, S., Sharma, V. K. Successful Treatment of Multiple Premalignant and Malignant Lesions in Arsenical Keratosis with a Combination of Acitretin and Intralesional 5-Fluorouracil. J Dermatol. 2003;30(10):730-734.
  6. Yerebakan, O., Ermis, O., Yilmaz, E., et al. Treatment of arsenical keratosis and Bowens disease with acitretin. Int J Dermatol. 2002;41(2):84-87.
  7. Park, J. Y., Rim, J. H., Choe, Y. B., et al. (2002). Arsenic Keratosis and Pigmentation Accompanied by Multiple Bowens Disease and Genitourinary Cancer in a Psoriasis Patient. J Dermatol. 2002;29(7):446-451.
  8. A case of arsenic keratosis in a patient from Newfoundland, Canada. J Am Acad Dermatol. 2015;72(5).
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  11. Acitretin: MedlinePlus Drug Information. (n.d.).
  12. Lehmann, P. Bowen’s disease – a review of newer treatment options. Ther Clin Risk Manag. 2008;4:1085-1095.
  13. Kadakia, Kunal C., et al. Randomized controlled trial of acitretin versus placebo in patients at high-risk for basal cell or squamous cell carcinoma of the skin (North Central Cancer Treatment Group Study 969251). Cancer. 2012;118(8):2128–2137.
  14. Bavinck JN, Tieben LM, Van der Woude FJ, et al. Prevention of skin cancer and reduction of keratotic skin lesions during acitretin therapy in renal transplant recipients: a double-blind, placebo-controlled study. J Clin Oncol. 1995;13:1933–1938.
  15. George R, Weightman W, Russ GR, et al. Acitretin for chemoprevention of non-melanoma skin cancers in renal transplant recipients. Australas J Dermatol. 2002;43:269–273.

AUTHOR CORRESPONDENCE

Brendon Verhave BS verhaveb@upstate.edu
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