Randomized, Investigator-Blinded Study to Compare the Efficacy and Tolerance of a 650-microsecond, 1064-nm YAG Laser to a 308-nm Excimer Laser for the Treatment of Mild to Moderate Psoriasis Vulgaris

February 2020 | Volume 19 | Issue 2 | Original Article | 176 | Copyright © February 2020


Published online January 9, 2020

Mark S. Nestor MD PhD,a Daniel Fischer DO MS,a David Arnold DOa

aCenter for Clinical and Cosmetic Research, Aventura, FL bDepartment of Dermatology and Cutaneous Surgery, Department of Surgery, Division of Plastic Surgery, University of Miami Miller School of Medicine, Miami, FL










The strength of the present study is its comparison with the excimer laser, the current first-line phototherapy for the treatment of mild to moderate psoriasis vulgaris. Results are nearly identical throughout the study and treatment-related adverse events were not observed. Limitations are the small number of patients and the short follow-up time. The encouraging results justify additional studies with more patients and longer follow-up time.

CONCLUSION

The efficacy and tolerance of the 650-microsecond laser has been shown to be equivalent to that of the excimer laser for the treatment of mild to moderate psoriasis vulgaris of the arms and legs.

DISCLOSURES

Dr. Nestor has received research grants from Aerolase and is a consultant to Aerolase. Drs. Fischer and Arnold have no disclosures.

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