Optimizing Topical Antifungal Therapy for Superficial Cutaneous Fungal Infections: Focus on Topical Naftifine for Cutaneous Dermatophytosis

November 2013 | Volume 12 | Issue 11 | Supplement Individual Articles | 165 | Copyright © November 2013


James Q. Del Rosso DO FAOCDa and Leon H. Kircik MDb

aTouro University College of Osteopathic Medicine, Henderson, NV;
Las Vegas Skin and Cancer Clinics/West Dermatology Group, JDRx Dermatology LLC, Henderson, NV
bMount Sinai Medical Center, New York, NY; Indiana University School of Medicine, Indianapolis, IN;
Physicians Skin Care, PLLC, Louisville, KY

The recent introduction of the 2% cream has been shown to be effective for tinea pedis and tinea cruris with once-daily application over a shorter duration (2 weeks) than what has been used in most cases with the 1% formulation. Although many of the available topical antifungal agents are effective and safe for CDIs and other SCFIs, naftifine offers fungicidal activity in most cases of CDIs, a rapid onset of clinical effect, and a therapeutic reservoir effect that may correlate with sustained clearance post-treatment.

DISCLOSURES

Dr. Del Rosso has served as a consultant, advisory board participant, clinical investigator, and/or speaker for Allergan, Bayer Healthcare (Dermatology), Dermira, Eisai, Ferndale, Galderma, Innocutis, LeoPharma, Liquidia, Merz Pharmaceuticals, Onset Dermatologics, Pharmaderm, Primus, Promius Pharma, PuraCap, Quinnova, Ranbaxy, Taro, Unilever, Valeant Pharmaceuticals (Medicis, Consumer Care), and Warner-Chilcott.
Dr. Kircik has served as an advisor, investigator, consultant, and speaker for Allergan, Galderma, Bayer Healthcare, LeoPharma, Merz Pharmaceuticals, Promius Pharma, Quinnova, Stiefel/GSK, Taro, Valeant, and Warner Chilcott.
This article was reviewed by Merz Pharmaceuticals as required for internal review. No questions emerged regarding accuracy or explanation of content. The paper was finalized solely by the authors, who wrote the manuscript and maintained full control over all the content. After submission to the journal, only the JDD editorial staff, dermatologists involved in the official peer-review process, and authors were involved with communications related to this manuscript. All final decisions on content were determined by the authors.

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AUTHOR CORRESPONDENCE

James Q. Del Rosso DO FAOCDjqdelrosso@yahoo.com
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