Dupilumab Improves Atopic Dermatitis and Post-Inflammatory Hyperpigmentation in Patient With Skin of Color

July 2020 | Volume 19 | Issue 7 | Case Reports | 776 | Copyright © July 2020

Published online June 24, 2020

Ciara Grayson MSa, Candice R. Heath MDb,c

aFlorida State University College of Medicine, Tallahassee, FL bLewis Katz School of Medicine, Temple University, Department of Dermatology, Philadelphia, PA

impact of the disease including the psychosocial burden, subsequent post-inflammatory hyperpigmentation and in some cases overall skin hyperpigmentation. Patients with atopic dermatitis experience higher rates of anxiety, depression, sleep disorders, and decreased work productivity.5 Additionally, the resulting post-inflammatory hyperpigmentation can negatively impact quality of life. The burden of atopic dermatitis in patients with skin of color goes way beyond pruritus. In our case, aggressive treatment with dupilumab resulted in improvement of the apparent hyperpigmentation in clinically non-lesional skin (but likely scientifically lesional skin), post-inflammatory hyperpigmentation and atopic dermatitis.


There are no potential perceived conflicts of interest and/or support, financial interests, or patents for Ciara Grayson.

Dr. Heath is a consultant for Sanofi-Regeneron and Pfizer.


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Ciara Grayson MS ciaragrayson5@gmail.com