The Effect of a Ceramide-Containing Product on Stratum Corneum Lipid Levels in Dry Legs

April 2020 | Volume 19 | Issue 4 | Original Article | 372 | Copyright © April 2020

Published online March 12, 2020

Zoe D. Draelos , Nada H. Baalbaki , Shelby Cook , Susana Raab , Gene Colón

aDermatology Consulting Services, PLLC bL'Oréal Research and Innovation, Clark NJ cL'Oréal USA, Inc. (CeraVe), New York, NY

efficacy by the study participants with >93% expressing overall satisfaction at all time points. These results and those from the stratum corneum lipid analysis are evidence for the benefits of using the studied ceramide-containing moisturizer for dry skin even in warmer, high-humidity conditions.


This 4-week, ceramide-containing moisturizer study was able to demonstrate an improved skin water content through corneometry, a reduction in subject perceived sensory discomfort, and dermatologist investigator assessed resolution of the signs of dry skin. Improvement continued for 48 hours after moisturizer withdrawal.


The study was funded by the L’Oréal Research & Innovation Dpt. Dr. Zoe Draelos received funding from L'Oréal to conduct the research presented in this manuscript. Nada Baalbaki, Shelby Cook, Susana Raab are employees of L’Oréal Research and Innovation. Gene Colón is an employee of L’Oréal USA, Inc. (CeraVe).


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Zoe Diana Draelos MD