Corneometry was used to assess skin water content. The water content of the skin increased after 3 days of study product use with a statistically significant 30.6% increase in the treated leg as compared to the control leg (P<.001). This improvement continued into week 4 with a 38% water content increase in the treated leg as compared to the untreated leg (P<.001). The increased water content was even maintained into the 48-hour regression phase where the skin had no moisturizer applied with a statistically significant 21.85% increase in water content comparing the treated to untreated leg (P<.01).
Immediately after application, the blinded investigator assessed