Atopic Dermatitis: A Review of Current Diagnostic Criteria and a Proposed Update to Management

March 2020 | Volume 19 | Issue 3 | Original Article | 244 | Copyright © March 2020


Published online February 4, 2020

Matthew Reynolds , Joe Gorelick , Matthew Bruno

aArkansas Dermatology and Skin Cancer Center, Little Rock, AR bCalifornia Skin Institute, San Jose, CA cDermatology and Skin Cancer Surgery Center, Allen, TX

the duration and age of onset of the essential and important features.

Subsequent treatment following a diagnosis of AD is reliant on treatment guidelines that reflect current knowledge. It is imperative, therefore, that AD treatment guidelines are updated regularly to reflect more accurately the risk–benefit profiles of systemic immunomodulators and to include newer treatment alternatives, particularly for moderate-to-severe AD cases. The advent of monoclonal antibodies aimed at targeting all aspects of the atopic disease spectrum may require us to revisit treatment algorithms, the implications of which would be far reaching, both for pharmaceutical drug development and in the establishment of guidelines for insurance-based drug formularies.

DISCLOSURES

Matthew Reynolds is a medical advisor and speaker for Sanofi- Regeneron; medical advisor for AbbVie Inc. and Eli Lilly and Company. Matthew Bruno is a medical advisor for AbbVie Inc., Dermira, Mayne Pharma, and PharmaDerm; and speaker and medical advisor for Almirall, S.A., Pfizer Inc., and Sun Pharmaceutical Industries Ltd. Joe Gorelick is a consultant, advisor, and speaker for AbbVie Inc., Beiersdorf, Celgene Corporation, Dermira, Eli Lilly and Company, Encore Dermatology Inc., Foamix Pharmaceuticals Ltd., LEO Pharma, Mayne Pharma, Novartis Pharmaceuticals, Ortho Dermatologics Inc., Primus Pharmaceuticals, PruGen Pharmaceuticals, Regeneron Pharmaceuticals, Inc., Sanofi-Genzyme, Sun Pharmaceutical Industries Ltd., and UCB S.A.

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AUTHOR CORRESPONDENCE

Matthew Reynolds PA-C mreynolds@arkansasdermatology.com