Do You Know the Most Complete, Targeted Biologic for Psoriasis? The Answer May Surprise You

August 2019 | Volume 18 | Issue 8 | Department | 200 | Copyright © August 2019

Kircik, L.H. et al.

Icahn School of Medicine at Mount Sinai, NY
Indiana Medical Center, Indianapolis, IN
Physicians Skin Care, PLLC, Louisville, KY
Skin Sciences, PLLC, Louisville, KY
DermResearch, PLLC, Louisville, KY

Abstract
When today’s dermatology residents were born, the concept of psoriasis as a systemic disease was relatively new. Early in the 1980s, topical therapy was the mainstay for medical management of this “skin condition.” Systemic therapies were beginning to be used for severe psoriasis, although it was unclear how they provided benefit. Three decades later, dermatologists have a much better—though perhaps still incomplete—understanding of the pathogenesis of psoriasis and its related comorbidities. Novel therapies have emerged to target the immunologic drivers at the heart of the disease