Secukinumab: Long-term Safety and Efficacy in Psoriasis

August 2017 | Volume 16 | Issue 8 | Supplement Individual Articles | 115 | Copyright © August 2017

Peter W. Hashim MD MHS,a Mark G. Lebwohl MD,a Leon H. Kircik MDa,b,c

aThe Icahn School of Medicine at Mount Sinai, Department of Dermatology, New York, NY bIndiana University School of Medicine, Indianapolis, IN cPhysicians Skin Care PLLC, Louisville, KY

Celgene, Valeant, Pfizer, Cellceutix, Promius, and Xenoport. Dr. Hashim has no conflicts.


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  24. Bissonnette R LT, Diamant T, Toth D, Letzelter K, Xia S, Mazur R, Milutinovic M, Leonardi C. Secukinumab Demonstrates Sustained High Efficacy and a Favorable Safety Profile in Moderate to Severe Psoriasis Patients Through 4 Years of Treatment. Oral presentation at: 25th European Academy of Dermatology and Venereology Congress, 28th September – 2nd October 2016, Vienna, Austria.
  25. Reich K, Blauvelt A, Armstrong A, Langley RG, Fox T, Huang J, et al. Secukinumab, a fully human anti-interleukin-17A monoclonal antibody, exhibits minimal immunogenicity in patients with moderate-to-severe plaque psoriasis. Br J Dermatol. 2016.
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  28. Gottlieb A SJ, Kubanov A, Tao A, Regnault P, Fox T, Milutinovic M, Frueh J. Secukinumab is Effective in Subjects With Moderate to Severe Palmoplantar Psoriasis: 1.5 Year Results From the GESTURE Study. Poster presented at: 25th European Academy of Dermatology and Venereology Congress, 28th September – 2nd October 2016, Vienna, Austria.
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  33. Reich K SJ, Arenberger P, Mrowietz U, Jazayeri S, Augustin M, Parneix A, Regnault P, You R, Milutinovic M. Secukinumab Shows Significant Efficacy in Nail Psoriasis: Week 32 Results from the TRANSFIGURE Study. Poster presented at: 25th European Academy of Dermatology and Venereology Congress, 28th September – 2nd October 2016, Vienna, Austria.
  34. McInnes IB KB, Mease P, Bhosekar V, Mpofu S, Gandhi K, Gaillez C on behalf of the FUTURE 2 study group. Secukinumab Provides Rapid and Sustained Reductions in Dactylitis, Enthesitis and Nail Psoriasis in Patients with Psoriatic Arthritis: 52-week Results of the FUTURE 2 study. Poster presented at: 25th European Academy of Dermatology and Venereology Congress, 28th September – 2nd October 2016, Vienna, Austria.
  35. Cosentyx [package insert]. East Hanover (NJ): Novartis Pharmaceuticals Corporation; 2016.


Leon H. Kircik MD