How Can We Change the Complexion of Acne and Rosacea?

June 2017 | Volume 16 | Issue 6 | Editorials | 531 | Copyright © June 2017

Del Rosso, J.Q.


observed clinically.11 From a medical therapy perspective, treatment of papulopustular rosacea warrants a combination of an agent directed against papulopustular lesions (ie, topical metronidazole, topical azelaic acid, topical ivermectin, and/or oral sub-antibiotic dose doxycycline) and a topical alpha-agonist directed against persistent non-transient facial erythema (ie, brimonidine, oxymetazoline). Physical devices may be integrated for treatment of telangiectasias and facial erythema. At the present time, although there are agents in development for acne and rosacea, our ability to improve management outcomes will depend on altering and optimizing our approaches to treatment using agents we currently have available. This includes the use of combination regimens and more aggressive management earlier during the course of disease. It will be important for research to increase in the development of newer agents that address novel MOAs, that can be integrated to optimize combination therapy, and that reduce or avoid antibiotic resistance. 

James Q. Del Rosso DO FAOCD FAAD

Research Director JDR Dermatology Research, Las Vegas, NV Dermatology and Cutaneous Surgery Thomas Dermatology, Las Vegas, NV


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