An Open Label Clinical Trial of a Peptide Treatment Serum and Supporting Regimen Designed to Improve the Appearance of Aging Facial Skin

September 2016 | Volume 15 | Issue 9 | Original Article | 1100 | Copyright © September 2016

Zoe Diana Draelos MD,a Tatiana Kononov BS MBA,b and Theresa Fox BSb

aDermatology Consulting Services, High Point, NC
bRevision Skincare, Irving, TX

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The only negative recurring comment was that the treatment regimen had too many products and was too time-consuming. This comment was expected with enrollment of a broad range of female consumers with varying skincare routines.

Efficacy of Products Other Than Serum: Subject Assessment at Week 14

The subjects were asked to assess the appearance of their skin for the products they used, other than the peptide treatment serum, at week 14 using the same scoring system noted above. They agreed that they had better skin texture (mean=0.90), more radiance (mean=1.17), more even skin tone (mean=1.34), less skin discoloration (mean=1.31), less redness (mean=1.34), less noticeable fine lines (mean=1.10), less noticeable wrinkles (mean=1.31), healthier-looking skin (mean=0.90), younger, firmer skin (mean=1.31), more moisturized skin (mean=0.62), and overall improved appearance (mean=0.86) when compared to baseline results.

Aesthetic Attributes of Serum: Subject Assessment at Week 14

The subjects were asked to assess the aesthetic attributes of only the peptide treatment serum at week 14 using the same numeric scale. The subjects agreed that the product absorbed well (mean=1.38) and that the smell (mean=1.00), texture (mean=0.66), and ease of application (mean=0.86) were excellent. They agreed that the product did not cause irritation (mean=0.62) and that they would purchase the product (mean=0.93).

Efficacy of Serum: Subject Assessment at Week 14 Eye Area

The subjects were asked to examine only the area around the eyes at 14 weeks and assess the peptide treatment serum using the numeric scale. They agreed that they had better skin texture (mean=1.07), more radiance (mean=1.14), improved fine lines (mean=1.21), improved wrinkles (mean=1.34), healthier-looking skin (mean=1.10), younger, firmer skin (mean=1.48), more moisturized skin (mean=0.83), and overall improved appearance (mean=1.07) around the eyes when compared to baseline results.
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