Acne Vulgaris in Skin of Color: Understanding Nuances and Optimizing Treatment Outcomes

June 2014 | Volume 13 | Issue 6 | Supplement Individual Articles | 61 | Copyright © June 2014

Andrew F. Alexis MD MPH

Skin of Color Center, Mount Sinai St. Luke’s Roosevelt Hospital, New York, NY
Icahn School of Medicine at Mount Sinai, New York, NY

  1. Identifying and eliminating potentially exacerbating factors that are more prevalent in specific populations (discussed above) is an important step toward ensuring favorable treatment outcomes.


The treatment of acne in skin of color patients involves selecting a regimen that ensures early and sustained control of inflammation; avoidance of irritation to prevent iatrogenic dyspigmentation; treatment of both acne lesions and associated PIH; and identification of potential cultural factors that can exacerbate or contribute to acne.


Andrew F. Alexis MD MPH has served as a consultant for Galderma, Allergan, Estée Lauder, Johnson & Johnson Consumer Companies Inc, L’Oréal, and SkinMedica.


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  6. Shah SK, Bhanusali DG, Sachdev A, Geria AN, Alexis AF. A survey of skin conditions and concerns in South Asian Americans: a community-based study. J Drugs Dermatol. 2011;10(5):524-528.
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  8. Shaffer JJ, Taylor SC, Cook-Bolden F. Keloidal scars: a review with a critical look at therapeutic options. J Am Acad Dermatol. 2002;46(2 Suppl Understanding):s63-s97.
  9. Alexis AF. Acne in patients with skin of color. J Drugs Dermatol. 2011;10(suppl 6):s13-s16.
  10. Alexis AF, Barbosa VH. Skin of Color: A Practical Guide to Dermatologic Diagnosis and Treatment. New York: Springer; 2013.
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  17. Thiboutot DM. Inflammasome activation by Propionibacterium acnes: the story of IL-1 in acne continues to unfold. J Invest Dermatol. 2014;134(3):595-597.
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  31. Alexis AF, Johnson LA, Kerrouche N, Callender VD. A subgroup analysis to evaluate the efficacy and safety of adapalene-benzoyl peroxide topical gel in black subjects with moderate acne. J Drugs Dermatol. 2014;13(2):170-174.
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  33. Callender VD. Fitzpatrick skin types and clindamycin phosphate 1.2%/benzoyl peroxide gel: efficacy and tolerability of treatment in moderate to severe acne. J Drugs Dermatol. 2012;11(5):643-648.
  34. Callender VD, Young CM, Kindred C, Taylor SC. Efficacy and safety of clindamycin phosphate 1.2% and tretinoin 0.025% gel for the treatment of acne and acne-induced post-inflammatory hyperpigmentation in patients with skin of color. J Clin Aesthet Dermatol. 2012;5(7):25-32.
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  40. Grimes P, Callender V. Tazarotene cream for postinflammatory hyperpigmentation and acne vulgaris in darker skin: a double-blind, randomized, vehicle-controlled study. Cutis. 2006;77(1):45-50.


Andrew F. Alexis MD