Efficacy of Combination of Glycolic Acid Peeling With Topical Regimen in Treatment of Melasma

October 2013 | Volume 12 | Issue 10 | Original Article | 1149 | Copyright © October 2013

Savita Chaudhary MD Fellow ISDa and Surabhi Dayal MDb

aDepartment of Dermatology, Era’s Lucknow Medical College and Hospital, Lucknow, India
bDepartment of Dermatology, Pt. BD Sharma, PGIMS, Rohtak, India

  1. Kligman AM, Willis I. A new formula for depigmenting human skin. Arch Dermatol 1975;111:40-8.
  2. Gano SE, Gracia RL. Topical tretinoin, hydroquinone and betamethasone valerate in the therapy of melasma. Cutis 1979;23:239-41.
  3. R.Chan, K.C Park, M.H Lee, E.S. Lee, S.E Chang, Y.H.Leow et al. A randomized controlled trial of efficacy and safety of a triple combination (flucinolone acetonide0.01%, hydroquinone 4%, tretinoin 0.05%) compared with hydroquinone 4% cream in Asian patients with moderate to severe melasma. Br J Dermatol 2008;159:697-703.
  4. Ni Z, Mu Y, Gulati O. Treatment of melasma with pycnogenol. Phytother Res 2002;16:567-71.
  5. Yamakoshi J, Sano A, Tokutake S, Saito M, Kikuchi M, Kubota Y et al. Oral intake of proanthocynanidin rich extract from grape seeds improve cholasma.Pthytother Res 2004;18:895-9.
  6. Savant SS, Mehta N. Superficial and medium depth chemical peeling. In:Savant SS, Atal- Shah R, Gore D, editors: Textbook and Atlas of Dermatsurgery and Cosmetology, 2nd edn. Philadelphia : WB Saunders Company 2005;177-95.
  7. Clark CP. Alpha hydroxy acidsin skin care. Clin Plastic Surgery 1996;23:49-56.
  8. Monheit GD, Kayal JD. Chemical peeling . In : Nouri K, Leal Khouri S, editors: Techniques in Dermatosurgery, 1stedn. St. Louis : Mosby 2004. p .233-44.
  9. Javaheri SM, Handa S, Kaur I, Kumar B. Safety and efficacy of glycolic acid facial peel in Indian with melasma. Int J Dermatol 2001;40:354-7.
  10. Garg VK, Sarkar R, Agarwal R. Comparative evaluation of beneficiary effect of priming agents (2% hydroquinone and 0.025% Retinoic acid) in the treatment of melasma with glycolic acid peels.Dermatol Surg 2008;34:1032-40.
  11. Erbil H, Sezer E, Tastan B, Arca E, Kurumlu. Efficacy and safey of serial glycolic acid peels and a topical regimen in the treatment of recalcirant melasma. J Dermatol 2007;34:25-30.
  12. Hurley ME, Guevara IL, Gonzales RM, Pandya AG. Efficacy of glycolic peels in the treatment of melasma. Arch Dermatol 2002;138:1578-82.
  13. Lim JT, Tham SN. Glycolic acid peels in the treatment of melasma among Asian women. Dermatol Sur 1997;23:177-9.
  14. Sarkar R, Kaur C, Bhalla M, Kanwar AJ. The combination of glycolic acid peels with a topical regimen in the treatment of melasma in dark skinned patients : A comparative study. Dermatol Surgery 2002;28:828-32.
  15. Kimbrough Green CK, Griffiths CE, Finkel LJ, Hamilton TA, Bulengo-Ramsby SM, Ellis CN et al. Topical retinoic acid (Tretinoin) for melasma in black patients. A vehicle controlled clinical trial. Arch Dermatol 1994;130:727-33.


Savita Chaudhary MD Fellow ISDsavitagarg3@gmail.com