Efficacy and Safety of Azelaic Acid (AzA) Gel 15% in the Treatment of Post-Inflammatory Hyperpigmentation and Acne: A 16-Week, Baseline-Controlled Study

June 2011 | Volume 10 | Issue 6 | Original Article | 586 | Copyright © June 2011


Leon H. Kircik, MD

Indiana University School of Medicine, Indianapolis, IN

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count was 46 percent at week 4 (P<0.0001) and 100 percent at week 16 (P=0.0002).
Similarly, there was a 45.5 percent median reduction in noninflammatory lesion counts at week 4 (P<0.0001) and a 100 percent median reduction at week 16 (P=0.0002).

Post-Inflammatory Hyperpigmentation

PIH Severity

At baseline, 60 percent of subjects were rated as having moderate PIH based on IGA, 20 percent had moderately severe
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