Mechanisms of Action of New Treatment Modalities for Actinic Keratosis

February 2006 | Volume 5 | Issue 2 | Original Article | 167 | Copyright © February 2006

Brian Berman MD PhD, Adariana M. Villa MD, Claudia C. Ramirez MD

Abstract
Actinic keratosis (AK) constitutes the initial lesion in a disease continuum that can progress to invasive squamous cell carcinoma (SCC). In this article, we describe the mechanisms of action, tolerability, and efficacy of the most frequently used chemopreventative, chemotherapeutic, destructive, and novel immunologic methods for the control and treatment of actinic keratoses.