Control of Diabetic Gustatory Hyperhidrosis With Topical 20% Aluminum Chloride Hexahydrate

December 2021 | Volume 20 | Issue 12 | Editorials | 1359 | Copyright © December 2021


Published online November 30, 2021

Jordan Tanner MD, Daniel Tinker MD, Dee Anna Glaser MD

Saint Louis University School of Medicine, St. Louis, MO

every third night adequately maintained control of symptoms. Most common side effects include irritation, stinging, burning, and dermatitis, especially on sensitive skin such as the face. It is important to counsel patients that aluminum chloride forms hydrochloric acid in the presence of water or active sweating.10 Pre-washing the face or application before prandial sweating can lead to highly irritated skin and treatment discontinuation. We recommend patients apply aluminum chloride at night to thoroughly dried skin, and to completely wash it off in the morning.

Proper application enhances efficacy and reduces the incidence of adverse effects commonly seen with aluminum chloride. Our case supports the use of aluminum chloride hexahydrate for diabetic gustatory hyperhidrosis based on its efficacy, availability, favorable side-effect profile and low cost.

DISCLOSURES

Dr. Glaser received research/grants from Allergan, Galderma, Revance, Evolus, Dermira, Atacama and served on the advisory position or speaker from Allergan, Galderma, Dermira, Candasent, and is President of International Hyperhidrosis Society. Jordan Tanner and Dr. Daniel Tinker report no conflicts of interest.

REFERENCES

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AUTHOR CORRESPONDENCE