Clinical Study Results of Desoximetasone Spray, 0.25% in Moderate to Severe Plaque Psoriasis

December 2013 | Volume 12 | Issue 12 | Original Article | 1404 | Copyright © December 2013


Leon Kircik MD,a,b,c Mark G. Lebwohl MD,c James Q. Del Rosso DO,d
Jerry Bagel MD,eLinda Stein Gold MD,f Jonathan S. Weiss MDg

aDepartment of Dermatology, Indiana University School of Medicine, Indianapolis, IN
bPhysicians Skin Care, PLLC, Louisville, KY
cDepartment of Dermatology, Mount Sinai School of Medicine, New York, New York
dDepartment of Dermatology, Touro University College of Osteopathic Medicine, Henderson, NV
ePsoriasis Treatment Center of Central New Jersey, East Windsor, NJ
fDirector of Dermatology, Clinical Research and Division Head of Dermatology, Henry Ford Health System, Detroit and West Bloomfield, Michigan
gGwinnett Clinical Research Center, Snellville, Georgia

Karl Heine MD, David Horowitz MD, Terry Jones MD, David James Kerr MD, Russell Mader MD, Jose Edward Mendez DO, Christopher Moeller MD, Edward John Primka MD, John Proffitt MD, Stephen Schleicher MD, Harry Sharata MD, Allan Soo MD, and Dow Stough MD.

DISCLOSURES

Drs. Kircik, Lebwohl, Del Rosso, Bagel, Stein Gold, and Weiss are consultants to Taro Pharmaceuticals.

REFERENCES

  1. Sulzberger MB, Witten VH.Effect of topically applied compound F in selected dermatoses. J Invest Dermatol. 1952;19:101-102.
  2. Data on file, Taro Pharmaceuticals Inc.
  3. Hengge UR.Topical corticosteroids. In: Gaspari AA, Tyring SK, Eds. Clinical and Basic Immunodermatology, Springer-Verlag, London, United Kingdom, 2008, pp. 561-577.
  4. Topicort Spray Package Insert
  5. Warner MR, Camisa C. Topical corticosteroids. In: Wolverton SE, Ed. Comprehensive Dermatologic Drug Therapy, 2nd Edition, Saunders-Elsevier, Philadelphia, USA, 2007, pp 595-624.
  6. Del Rosso J, Friedlander SF. Corticosteroids: options in the era of steroid sparing therapy. J Am Acad Dermatol. 2005;53:850-858.
  7. Brown F, Wilkinson SM. Effective prescribing in steroid allergy: Controversies and cross-reactions. Clin Derm. 2011;29:287-294.
  8. BaeckM, Marot L, Nicolas JF, et al. Allergic hypersensitivity to topical and systemic corticosteroids: a review. Allergy. 2009;64:978-994.
  9. Zeichner JA, Lebwohl MG, Menter A, et al. Optimizing topical therapies for treating psoriasis: a consensus conference. Cutis. 2010;86(3 Suppl):5-31.
  10. Samarasekera EJ, Sawyer L, Wonderling D, et al. Topical therapies for the treatment of plaque psoriasis: systematic review and network meta-analyses. Br J Dermatol. 2013;168(5):954-967.
  11. Mason AR, Mason J, Cork M, Dooley G, et al. Topical treatments for chronic plaque psoriasis. Cochrane Database Syst Rev. 2013 Mar 28;3:CD005028. doi: .1002/14651858.CD005028.pub3.
  12. Hsu S, Papp KA, Lebwohl MG, et al. Consensus guidelines for the management of plaque psoriasis. Arch Dermatol. 2012;148(1):95-102

Author Correspondence

Leon Kircik MDwedoderm@yahoo.com
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