Found 177 articles for: "melasma"
Clinical Efficacy and Safety of a Multimodality Skin Brightener Composition Compared With 4% Hydroquinone
March 2013 | Volume 12 | Issue 3 | Supplement Individual Articles | 21 | Copyright © March 2013
There are numerous common skin disorders involving hyperpigmentation, including solar lentigines, postinflammatory hyperpigmentation, melasma, freckles, and dyschromia from photoaging. While these con...
Read MoreEvaluation of a Hydroquinone-Free Skin Brightening Product Using In Vitro Inhibition of Melanogenesis and Clinical Reduction of Ultraviolet-Induced Hyperpigmentation
March 2013 | Volume 12 | Issue 3 | Supplement Individual Articles | 16 | Copyright © March 2013
BACKGROUND and OBJECTIVE: Skin lightening preparations are used by people all over the world for a diverse range of dermatologic indications. Hydroquinone (HQ) is the gold standard and remains the onl...
Read MoreComparison of a Skin-Lightening Cream Targeting Melanogenesis on Multiple Levels to Triple Combination Cream for Melasma
March 2013 | Volume 12 | Issue 3 | Original Article | 270 | Copyright © March 2013
The safety and efficacy of a novel skin-lightening cream (SLC) with 4% hydroquinone (HQ), which additionally contains 4 skin-brightening actives, was compared with a triple combination cream (TCC) wit...
Read MoreA Potential Role for miRNAs in Topical Drug Development
February 2013 | Volume 12 | Issue 2 | Editorials | 152 | Copyright © February 2013
Successful Short-Term and Long-Term Treatment of Melasma and Postinflammatory Hyperpigmentation Using Vitamin C With a Full-Face Iontophoresis Mask and a Mandelic/Malic Acid Skin Care Regimen
January 2013 | Volume 12 | Issue 1 | Original Article | 45 | Copyright © January 2013
Background: Treatment of melasma and postinflammatory hyperpigmentation is often challenging. No ideal short-term and long-term treatment is available. Vitamin C alone and in combinat...
Read MoreMessage From the Guest Editor
January 2013 | Volume 12 | Issue 1 | Editorials | 12 | Copyright © January 2013
Clinical Efficacy and Safety of a Multimodality Skin Brightener CompositionCompared With 4% Hydroquinone
December 2012 | Volume 11 | Issue 12 | Original Article | 1478 | Copyright © December 2012
There are numerous common skin disorders involving hyperpigmentation, including solar lentigines, postinflammatory hyperpigmentation, melasma, freckles, and dyschromia from photoaging. While these co...
Read MoreTreatment of Melasma and the Use of Intense Pulsed Light: A Review
November 2012 | Volume 11 | Issue 11 | Original Article | 1316 | Copyright © November 2012
Melasma is a complex multifactorial disorder whose pathogenesis is not well understood. In addition to increased pigmentation, increased vascularity associated with pigmentation is present. A variety ...
Read MoreThe Evolution of Quality-Switched Lasers
November 2012 | Volume 11 | Issue 11 | Original Article | 1296 | Copyright © November 2012
Quality-switched (QS) lasers and their applications have evolved greatly since the ruby laser's effect on tattoo ink was first reported in the 1960s. The 1983 description of selective photothermolysi...
Read MoreFractional Laser Skin Resurfacing
November 2012 | Volume 11 | Issue 11 | Original Article | 1274 | Copyright © November 2012
Laser skin resurfacing (LSR) has evolved over the past 2 decades from traditional ablative to fractional nonablative and fractional ablative resurfacing. Traditional ablative LSR was highly effective...
Read MoreDeoxyArbutin and Its Derivatives Inhibit Tyrosinase Activity and Melanin Synthesis Without Inducing Reactive Oxygen Species or Apoptosis
October 2012 | Volume 11 | Issue 10 | Original Article | 28 | Copyright © October 2012
Safety is a major concern in developing commercial skin-lightening agents. Here, we report the modulating effects of deoxyArbutin (dA) and its second-generation derivatives—deoxyFuran (dF), 2-fl...
Read MoreMicrodermabrasion: Molecular Mechanisms Unraveled, Part 2
September 2012 | Volume 11 | Issue 9 | Original Article | 10 | Copyright © September 2012
Microdermabrasion (MDA) remains a common in-office procedure for many dermatologic practices. The procedure offers minimal downtime with a low incidence of side effects, making it a relatively desirab...
Read MoreEfficacy and Tolerability of Two Commercial Hyperpigmentation Kits in the Treatment of Facial Hyperpigmentation and Photo-Aging
August 2012 | Volume 11 | Issue 8 | Original Article | 964 | Copyright © August 2012
Background: Hyperpigmentary disorders are common aesthetic skin conditions that can be very concerning to patients and both challenging and time-consuming for the physician to treat. Several co...
Read MoreTreatment of Mild to Moderate Facial Melasma With the Lumixyl Topical Brightening System
May 2012 | Volume 11 | Issue 5 | Case Reports | 660 | Copyright © May 2012
Background: Melasma is a cutaneous disorder associated with an overproduction of melanin by the tyrosinase enzyme...
Read MoreTop Dermatologic Conditions in Patients of Color: An Analysis of Nationally Representative Data
April 2012 | Volume 11 | Issue 4 | Original Article | 466 | Copyright © April 2012
Background: Some dermatologic disorders are known to be much more common in patients of color, but the leading de...
Read MoreTreatment of Moderate to Severe Acne Vulgaris in a Hispanic Population: A Post-Hoc Analysis of Efficacy and Tolerability of Clindamycin Phosphate 1.2%/Benzoyl Peroxide 2.5% Gel
April 2012 | Volume 11 | Issue 4 | Original Article | 455 | Copyright © April 2012
Background: Acne in Hispanics is an increasing problem, presenting unique challenges. Although combination therap...
Read MoreClinical Trial Review
January 2012 | Volume 11 | Issue 1 | Features | 134 | Copyright © January 2012
Clinical Trial Review is a JDD department designed to provide physicians with information on drugs and devices undergoing clinical testing. It is our goal to inform the reader of the status of select ...
Read MoreSafety and Efficacy Evaluation of Tretinoin Cream 0.02% for the Reduction of Photodamage: A Pilot Study
January 2012 | Volume 11 | Issue 1 | Original Article | 83 | Copyright © January 2012
Background: Clinical studies as well as histologic data maintain that tretinoin improves the appearance of photodamage; however, the long-term benefits of tretinoin 0.02% in moderate to severe ...
Read MoreSplit-Face Study of Topical 23.8% L-Ascorbic Acid Serum in Treating Photo-Aged Skin
January 2012 | Volume 11 | Issue 1 | Original Article | 51 | Copyright © January 2012
Background: L−ascorbic acid has been widely used to treat photo-aged skin. However, its aqueous formula is ...
Read MoreComparison Between 1% Tretinoin Peeling Versus 70% Glycolic Acid Peeling in the Treatment of Female Patients With Melasma
December 2011 | Volume 10 | Issue 12 | Original Article | 1439 | Copyright © December 2011
Melasma is an irregular brownish pigmentation observed on the faces of young to middle-aged women, especially of Asian races, which may contribute to various emotional disturbances. Although not any f...
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